Reduction in the rate of postoperative delirium by switching from famotidine to omeprazole in Japanese hepatectomized recipients

Table 4 Postoperative J-NCS score in famotidine and omeprazole groups

J-NCS score	0 ~ 19	20 ~ 24		25 ~ 26
J-NCS score	famotidine (n = 5)	famotidine (n = 4)	omeprazole (n = 3)	famotidine (n = 1)	omeprazole (n = 8)
subscale 1 (14 points) (Recognition-information processing)	7.4 ± 1.7	11.0 ± 2.0	11.0 ± 1.0	14	13.8 ± 0.46
subscale 2 (10 points) (Behavior)	5.6 ± 3.0	7.8 ± 0.96	7.7 ± 0.58	9	9.6 ± 0.52
subscale 3 (6 points) (Physiologic control)	2.2 ± 0.84	2.8 ± 0.50	3.3 ± 1.2	3	2.3 ± 0.46

J-NCS score was evaluated at 10 PM each day (total 4 days) after hepatectomy, and the lowest score in each recipient was used
The J-NCS score of 24 or less was defined as the condition of delirium onset
Significant difference (P < 0.05): In subscale 1, famotidine(0~19) vs omeprazole (25~26), and omeprazole (20~24) vs omeprazole (25~26)
In subscale 2: famotidine(0~19) vs omeprazole (25~26),: famotidine(20~24) vs omeprazole (25~26), and omeprazole (20~24) vs omeprazole (25~26)
In subscale 3: no significant difference each other
Statistical analyses were made by using Steel-Dwass method for nonparametric multiple comparison test

ISSN: 2055-0294