Table 5 Drugs reduced and improved adverse drug reactions due to pharmacist interventions for cancer patients who did not use opioids
n | (%) | ||
|---|---|---|---|
Pharmacological categories of drugs reduced by pharmacist recommendations | |||
Gastrointestinal medications | 126 | (35.1) | |
Antiemetics | 88 | (24.5) | |
Hypnotic sedatives | 83 | (23.1) | |
Analgesics | 81 | (22.6) | |
Laxatives | 60 | (16.7) | |
Antipsychotics | 31 | (8.6) | |
Other | 41 | (11.4) | |
Drugs reduced in each pharmacological category (multiple answers from options) | |||
Antiemetics | Prokinetic agents | 52 | (14.5) |
Dopamine receptor antagonists | 50 | (13.9) | |
Antihistaminic agents | 15 | (4.2) | |
Other | 5 | (1.4) | |
Gastrointestinal medications | Histamine H2 receptor blockers | 69 | (19.2) |
Proton pump inhibitors | 58 | (16.2) | |
Gastric antacids | 33 | (9.2) | |
Prostaglandin analogs | 10 | (2.8) | |
Other | 26 | (7.2) | |
Hypnotic sedatives | Benzodiazepines | 81 | (22.6) |
Non-benzodiazepines | 26 | (7.2) | |
Analgesics | Non-steroidal anti-inflammatory drugs | 61 | (17.0) |
Analgesic adjuvants | 23 | (6.4) | |
Acetaminophen | 21 | (5.8) | |
Laxatives | Salt-based laxative | 47 | (13.1) |
Peroral stimulative laxatives | 21 | (5.8) | |
Small intestine irritant laxative | 3 | (0.8) | |
Other | 2 | (0.6) | |
Antipsychotics | Typical antipsychotics | 31 | (8.6) |
Atypical antipsychotics | 22 | (6.1) | |
Others | Hypertensives | 15 | (4.2) |
Vitamins | 8 | (2.2) | |
Antibiotics | 5 | (1.4) | |
Drugs for high cholesterol | 5 | (1.4) | |
Medications for intestinal disorders | 4 | (1.1) | |
Diuretics | 3 | (0.8) | |
Antihyperuricemics | 3 | (0.8) | |
Antidiabetics | 3 | (0.8) | |
Chinese herbal medicine | 3 | (0.8) | |
Anticoagulants | 1 | (0.3) | |
Antiepileptic drugs | 1 | (0.3) | |
Gargle medicines | 1 | (0.3) | |
Other | 1 | (0.3) | |
Symptoms improved due to pharmacist interventions (free multiple answers) | |||
Electrolyte abnormality | 20 | (5.6) | |
Delirium | 14 | (3.9) | |
Hypotension | 14 | (3.9) | |
Renal dysfunction | 12 | (3.3) | |
Extrapyramidal symptoms | 9 | (2.5) | |
Sleepiness | 9 | (2.5) | |
Liver dysfunction | 9 | (2.5) | |
Constipation | 8 | (2.2) | |
Dizziness | 8 | (2.2) | |
Hypoglycemia | 4 | (1.1) | |
Nausea and vomiting | 3 | (0.8) | |
Sleep disorder | 3 | (0.8) | |
Gastrointestinal disorder | 3 | (0.8) | |
Bleeding | 2 | (0.6) | |
Dysuria | 2 | (0.6) | |
Myasthenia gravis | 1 | (0.3) | |
Edema | 1 | (0.3) | |
Tiredness | 1 | (0.3) | |
Dehydration | 1 | (0.3) | |
Hyperglycemia | 1 | (0.3) | |
Fever | 1 | (0.3) | |
Bradycardia | 1 | (0.3) | |
Thrombosis | 1 | (0.3) | |
Digoxin intoxication | 1 | (0.3) | |