Skip to main content
Fig. 1 | Journal of Pharmaceutical Health Care and Sciences

Fig. 1

From: Continuous high-dose infusion of doripenem in a pneumonia patient infected by carbapenem-resistant Pseudomonas aeruginosa: a case report

Fig. 1

Time course of values for doripenem and other laboratory tests. The concentration of unbound doripenem in serum was 47.8 μg/mL at 20 h after dosing was started, and decreased to 33.6 μg/mL at 111 h. All biomarkers that acted as an indicator of infection were included in the calculations for the respective normal ranges. The serum concentration of tobramycin was measured on Day 1 before the admission of the patient to the ICU (peak, 16.5 μg/mL; trough, 4.3 μg/mL); the tobramycin dose was then decreased from 5.3 mg/kg/day to 2.7 mg/kg/day. CRP, C-reactive protein; CRRT, continuous renal replacement therapy; AN69-ST, a dialyzer membrane made by polyacrylonitrile (surface-treated)

Back to article page