Table 1 Composition and behavior in Humulin®R and NovoRapid®
Formulation | Main medication | pH | Additives (in 100 U/ mL) | ||
|---|---|---|---|---|---|
Humulin®R | Human insulin (5807.57) | 7.0–7.8 | zinc | 0.015 mg | (65.38) |
m-cresol | 2.5 mg | (108.14) | |||
glycerin | 16 mg | (92.09) | |||
pH regulator | – | – | |||
NovoRapid® | Insulin aspart (5825.54) | 7.2–7.6 | zinc | 0.0196 mg | (65.38) |
m-cresol | 1.72 mg | (108.14) | |||
phenol | 1.50 mg | (94.11) | |||
glycerin | 16 mg | (92.09) | |||
disodium hydrogen phosphate dihydrate | 1.25 mg | (177.99) | |||
sodium chloride | 0.58 mg | (58.44) | |||
hydrochloric acid | – | (36.46) | |||
sodium hydrate | – | (40.00) | |||