Evaluation of the efficacy of drug treatment based on measurement of the oxidative stress, using reactive oxygen metabolites and biological antioxidant potential, in children with autism spectrum disorder and attention deficit hyperactivity disorder

Table 2 The pre- to post-treatment changes in objective markers and subjective scores

All subjects	Before	After	Change^a	p ^b
d-ROMs(U.CARR)	413.1	363.3	49.8	<.001
BAP (μmol/L)	2521.5	2403.3	118.2	0.007
BAP/d-ROMs	6.16	6.65	−0.50	<.001
ADHD-RS	27.4	15.40	12.00	<.001
PARS-TR	21.3	13.2	8.18	<.001
4–6 years
d-ROMs(U.CARR)	443.8	381.6	62.2	0.004
BAP (μmol/L)	2679.6	2467.4	212.1	0.05
BAP/d-ROMs	6.13	6.51	−0.38	0.13
ADHD-RS	24.7	17.4	7.22	0.14
PARS-TR	19.4	12.3	7.11	0.008
7–14 years
d-ROMs(U.CARR)	406.3	359.2	47.1	<.001
BAP (μmol/L)	2486.8	23,891.2	97.6	0.03
BAP/d-ROMs	6.16	6.68	−0.52	<.001
ADHD-RS	28.0	15.0	13.00	<.001
PARS-TR	21.7	13.3	8.4	<.001

^aChange is the score obtained by subtracting the score after treatment from the score before treatment
^b Wilcoxon signed-rank test was used to compute p-values

ISSN: 2055-0294