Table 3 Multivariate Cox regression model for hypoglycemia risk
| Â | No. of cases | Person-years | Incidence rate per 100 population | HR | 95% CI | P-value |
|---|---|---|---|---|---|---|
Sitagliptin | ||||||
monotherapy | 3 | 378 | 0.8 | 1.00 | Â | Â |
 + SU | 40 | 718 | 5.6 | 4.42 | (1.36–14.42) | 0.014 |
 + TZD | 16 | 326 | 4.9 | 0.55 | (0.23–1.34) | 0.189 |
 + GLINIDE | 0 | 29 | 0.0 |  |  |  |
 + AGI | 15 | 193 | 7.8 | 0.90 | (0.37–2.22) | 0.820 |
 + BIGUANIDE | 27 | 566 | 4.8 | 0.83 | (0.35–2.01) | 0.685 |
Antihypertensive agents | ||||||
 + β-blocker | 11 | 157 | 7.0 | 3.50 | (1.54–7.96) | 0.003 |
 + Diuretic | 4 | 111 | 3.6 | 1.67 | (0.56–4.96) | 0.359 |
 + ACE/ARB | 22 | 681 | 3.2 | 0.91 | (0.42–1.97) | 0.819 |
 + CCB | 17 | 541 | 3.1 | 0.97 | (0.45–2.11) | 0.942 |