Characteristic | Univariate analysis | Multivariate analysis | ||||
---|---|---|---|---|---|---|
OR | 95% CI | P value | OR | 95% CI | P value | |
Age (years) | 1.005 | 1.001–1.009 | 0.024 * | 1.006 | 1.001–1.011 | 0.017 * |
Sex (male) | 1.290 | 1.049–1.586 | 0.016 * | 1.221 | 0.984–1.515 | 0.069 |
Duration of vancomycin treatment (days) | 1.056 | 1.038–1.074 | < 0.001 * | 1.059 | 1.041–1.078 | < 0.001 * |
Number of hospital beds | ||||||
≤ 199 beds | 0.358 | 0.245–0.524 | < 0.001 * | 0.299 | 0.197–0.452 | < 0.001 * |
200–499 beds | 1.103 | 0.875–1.390 | 0.408 | 1.079 | 0.831–1.399 | 0.569 |
≥ 500 beds | 1.269 | 1.028–1.567 | 0.027 * | – | – | – |
Clinical departments of prescription of vancomycin | ||||||
Internal Medicine | 1.099 | 0.899–1.343 | 0.357 | 1.162 | 0.917–1.472 | 0.214 |
Respiratory Medicine | 1.436 | 0.937–2.200 | 0.097 | 1.473 | 0.925–2.344 | 0.103 |
Pediatrics | 0.513 | 0.302–0.871 | 0.013 * | 0.680 | 0.365–1.267 | 0.224 |
Other internal medicine | 2.568 | 1.287–5.126 | 0.007 * | 2.854 | 1.385–5.881 | 0.004 * |
Cardiology | 0.697 | 0.258–1.881 | 0.476 | 1.090 | 0.379–3.133 | 0.873 |
Other departments | 0.812 | 0.653–1.011 | 0.062 | – | – | – |
Ward pharmacy service | 1.477 | 1.210–1.803 | < 0.001 * | 1.514 | 1.232–1.861 | < 0.001 * |