Effect of xanthan gum-based food thickeners on the dissolution profile of fluoroquinolones oral formulations

Table 1 Excipients in fluoroquinolone-based formulations

Dosage form	TFLX			LVFX	CPFX
Dosage form	Tablets	Uncoated fine granules	Film-coated fine granules	Tablets	Tablets
Film coating agent	Hypromellose	None	Polyvinyl alcohol/acrylic acid/methyl methacrylate copolymer	Hypromellose	Hypromellose
Other	L-aspartic acid, crystalline cellulose, corn starch, hydrous silicon dioxide, hydroxypropylcellulose, magnesium stearate, polyoxyethylene (105) polyoxypropylene (5) glycol, talc, titanium oxide, carnauba wax	Sucrose, aspartame, hydroxypropylcellulose, hydrous silicon dioxide, iron sesquioxide, fragrance	Refined sucrose, L-aspartic acid, aspartame, iron sesquioxide, hydrous silicon dioxide, fragrance	Crystalline cellulose, carboxymethyl cellulose, hydroxypropyl cellulose, sodium stearyl fumarate, titanium oxide, talc, macrogol 6000, yellow ferric oxide, iron sesquioxide, carnauba wax	Crystalline cellulose, corn starch, crospovidone, light anhydrous silicic acid, magnesium stearate, macrogol 4000, titanium oxide

ISSN: 2055-0294