Effect of xanthan gum-based food thickeners on the dissolution profile of fluoroquinolones oral formulations

Table 2 Dissolution-rate conformance and similarity of fluoroquinolone-based formulations containing 1.5% (w/v) XG-FT with the reference

Dosage form	TFLX				LVFX		CPFX
Dosage form	Tablets	Crushed tablets	Uncoated fine granules	Film-coated fine granules	Tablets	Crushed tablets	Tablets	Crushed tablets
Conformance to specification	Yes	Yes	Yes	Yes	Yes	Yes	No	No
Judgement of similarity	No	No	No	Yes	Yes	No	No	No

ISSN: 2055-0294