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Table 4 Factors associated with the inappropriate dosing of direct oral anticoagulants in multivariate analysis

From: Inappropriate direct oral anticoagulant dosing in atrial fibrillation patients is associated with prescriptions for outpatients rather than inpatients: a single-center retrospective cohort study

Predictor variables

Odds ratio

95% confidence interval

P value

Outpatients (vs. inpatients)

2.87

1.53–5.62

< 0.001

HAS-BLED score*

1.87

1.42–2.51

< 0.001

  1. *Odds ratio per point increase
  2. Type of hospital visit (outpatients or inpatients), history of bleeding, myocardial infarction, cerebrovascular disease, polypharmacy, single antiplatelet therapy, CHADS2 score, CHA2DS2-VASc score, and HAS-BLED score, which were factors associated (p < 0.1) with inappropriate direct oral anticoagulant prescription in univariate analysis, were included in multivariate logistic regression analysis with a stepwise procedure