| |
α
|
β
|
95% CI
|
p-value
|
VIF
|
|---|
|
Constant
|
-2.026
| | | | |
|
Body weight
|
0.185
|
0.346
|
0.139 - 0.533
|
<0.001
|
1.039
|
|
LDH
|
0.004
|
0.272
|
0.086 - 0.478
|
0.006
|
1.037
|
Interacting drug use
(VPA or amiodarone)
|
2.961
|
0.543
|
0.306 - 0.700
|
<0.001
|
1.042
|
- C/D serum concentration/dose, VPA valproic acid, PB phenobarbital, LDH lactate dehydrogenase, α partial regression coefficient, β standardized partial regression coefficient, CI confidence interval, VIF variance inflation factor
- Multiple linear regression analysis (forward stepwise selection method) and regression equation was found.
- The explanatory variables were selected according to a significant correlation with the weight-corrected PB C/D ratio using single linear regression analysis.
- Weight-corrected PB C/D ratio = -2.026 + 2.961 × [interacting drug use: (1=no, 2=yes)] + 0.185 × [body weight (kg)] +0.004 × [LDH (U/L)]
