| | α | β | 95% CI | p-value | VIF |
|---|
Constant | -2.026 | | | | |
Body weight | 0.185 | 0.346 | 0.139 - 0.533 | <0.001 | 1.039 |
LDH | 0.004 | 0.272 | 0.086 - 0.478 | 0.006 | 1.037 |
Interacting drug use (VPA or amiodarone) | 2.961 | 0.543 | 0.306 - 0.700 | <0.001 | 1.042 |
- C/D serum concentration/dose, VPA valproic acid, PB phenobarbital, LDH lactate dehydrogenase, α partial regression coefficient, β standardized partial regression coefficient, CI confidence interval, VIF variance inflation factor
- Multiple linear regression analysis (forward stepwise selection method) and regression equation was found.
- The explanatory variables were selected according to a significant correlation with the weight-corrected PB C/D ratio using single linear regression analysis.
- Weight-corrected PB C/D ratio = -2.026 + 2.961 × [interacting drug use: (1=no, 2=yes)] + 0.185 × [body weight (kg)] +0.004 × [LDH (U/L)]
