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Table 4 Drug-related problems (DRPs) identified and classes of medications involved in the occurrence of DRPs among neonates with sepsis

From: Drug-related problems and its determinant among hospitalized neonates with sepsis at Jimma University Medical Center, Ethiopia: a prospective observational study

Variables

Frequency (%)

Neonates with drug-related problem

98 (48.8)

Drug-related needs and classification of DRPs

Indication

Unnecessary drug therapy

7 (5.7)

Need an additional drug therapy

40 (33.5)

Effectiveness

Ineffective drug therapy

2 (1.6)

Dose too low

24 (19.8)

Safety

Dose too high

42 (34.7)

Adverse drug reaction

3 (2.5)

Non-compliance

Non-adherence

3 (2.5)

Total number of DRPs identified

121 (100)

Class of medications involved in DRPs

Antibiotics

52 (42.9)

Analgesics-Antipyretics

36 (29.7)

Antiepileptic

17 (14.0)

Maintenance fluid

7 (5.7)

Vitamin k

4 (3.3)

Ferrous sulfate/folic acid

3 (2.4)

Others

2 (1.6)

Total

121 (100)

  1. DRPs drug-related problems