| pre-AS period | post-AS period | p-value |
---|---|---|---|
 | (n = 288) | (n = 247) |  |
Age (years) | 81.9 ± 13.8 | 82.9 ± 12.2 | 0.281 |
Sex (F/M) | 129/159 | 111/136 | 0.973 |
Body weight (Kg) | 47.0 ± 13.8 | 46.8 ± 14.3 | 0.435 |
CCr (mL/min) | 46.2 ± 30.7 | 45.4 ± 30.0 | 0.363 |
Focus of infection | |||
 Respiratory | 148 (51) | 152 (62) | 0.212 |
 Urinary tract | 75 (26) | 44 (18) | 0.068 |
 Gastrointestinal and Intraabdominal | 38 (13) | 27 (11) | 0.479 |
 Bone and soft tissue | 17 (6) | 13 (5) | 0.762 |
 Others | 10 (4) | 12 (5) | 0.440 |