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Table 4 Changes in AUD, DOT, and the AUD/DOT ratio between pre- and post-AS periods

From: Impact of an antimicrobial stewardship in a 126-bed community hospital with close communication between pharmacists working on post-prescription audit, ward pharmacists, and the antimicrobial stewardship team

 

Carbapenem

TAZ/PIPC

pre-AS

post-AS

p-value

pre-AS

post-AS

p-value

AUD

8.28 ± 3.39

3.67 ± 1.73

< 0.05

15.05 ± 5.91

8.55 ± 3.47

< 0.05

DOT

21.62 ± 7.23

5.88 ± 1.76

< 0.01

20.93 ± 8.76

12.65 ± 4.96

< 0.05

AUD/DOT

0.37 ± 0.07

0.60 ± 0.12

< 0.01

0.73 ± 0.08

0.67 ± 0.07

0.15

  1. Values are presented as means±SD
  2. AUD: Antimicrobial use density (DDDs/1000 patient-days), DOT: Days of therapy (DOTs/1000 patient-days)
  3. Data were analyzed using the Mann-Whitney U-test