Fig. 1

The effects of 4 days’ CPT-11 treatment in rats. The panels show the rates of change in body weight (a), food intake (b), fecal count (c), and fecal mass (b) throughout the CPT-11 treatment. The open circles represent the control group (n = 14, the intravenous administration of 3 mL/kg saline). The closed circles represent the CPT-11-treated group (n = 14, the intravenous administration of 60 mg/kg CPT-11). Data are shown as the mean ± SD. **p < 0.01