Fig. 2From: Digoxin absorption decreased independently of P-gp activity in rats with irinotecan-induced gastrointestinal damagePlasma concentration-time curves of DGX after its oral administration at 40 μg/kg (a), (b) or its intravenous administration at 30 μg/kg (c). The insets in (a) and (c) show semi-logarithmic plots. (b) shows the enlarged figure of (a) until 3 h after oral administration of DGX. The open and closed circles represent the control and CPT-11-treated groups, respectively. The circles and squares represent the DGX alone and DGX + CAM treated groups, respectively. Data are shown as the mean ± SD. (n = 7)Back to article page