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Fig. 2 | Journal of Pharmaceutical Health Care and Sciences

Fig. 2

From: Digoxin absorption decreased independently of P-gp activity in rats with irinotecan-induced gastrointestinal damage

Fig. 2

Plasma concentration-time curves of DGX after its oral administration at 40 μg/kg (a), (b) or its intravenous administration at 30 μg/kg (c). The insets in (a) and (c) show semi-logarithmic plots. (b) shows the enlarged figure of (a) until 3 h after oral administration of DGX. The open and closed circles represent the control and CPT-11-treated groups, respectively. The circles and squares represent the DGX alone and DGX + CAM treated groups, respectively. Data are shown as the mean ± SD. (n = 7)

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