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Table 2 Diarrhea score after the administration of CPT-11 for 4 days

From: Digoxin absorption decreased independently of P-gp activity in rats with irinotecan-induced gastrointestinal damage

Group

Score

Mean

0

1

2

3

Control (n = 14)

14

0

0

0

0

CPT-11-treated (n = 14)

1

3

2

8

2.2**

  1. **p < 0.01