Patients (n = 59) | Courses (n = 475) | |||
---|---|---|---|---|
Gender (male/female) | 33/26 | 307/168 | ||
Age, median (range) | 69 | (38–84) | 69 | (38–84) |
Albumin (g/dL) | 4 | (3.7–4.2) | 4 | (3.7–4.2) |
Aspartate aminotransferase (U/L) | 24 | (19–30) | 25 | (19–33) |
Alanine aminotransferase (U/L) | 21 | (15–28.5) | 20 | (14–29) |
Serum creatinine (mg/dL) | 0.61 | (0.51–0.76) | 0.63 | (0.52–0.80) |
Total bilirubin (mg/dL) | 0.5 | (0.4–0.7) | 0.5 | (0.4–0.6) |
C-reactive protein (CRP, mg/dL) | 0.3 | (0.06–1.13) | 0.22 | (0.08–0.65) |
Neutrophils (/μL) | 2570 | (1735–3298) | 2510 | (1760–3480) |
White blood cells (/μL) | 4250 | (3155–5255) | 4400 | (3485–5905) |
Hemoglobin (g/dL) | 10.6 | (9.9–11.5) | 10.6 | (9.7–116) |
Platelets (/μL) | 17.5 | (12.6–26.1) | 18.95 | (12.9–29.3) |
Neutrophil/lymphocyte ratio (NLR) | 1.91 | (1.41–3.18) | 1.99 | (1.39–3.12) |
Modified Glasgow prognostic score (mGPS, 0/1/2) | 43/9/7 | 376/58/21 | ||
Carcinoembryonic antigen (CEA, ng/mL) | 6.2 | (2.7–9.7) | 4.6 | (2.8–8.3) |
Carbohydrate antigen 19–9 (CA19–9, U/mL) | 655.1 | (54.0–2691) | 166.1 | (39.8–1228) |
Chemotherapy, N (%) | ||||
FOLFIRINOX | 20 | (33.9%) | 179 | (37.7%) |
Gemcitabine plus nab-paclitaxel (GnP) | 27 | (45.8%) | 227 | (47.8%) |
Gemcitabine monotherapy | 12 | (20.3%) | 69 | (14.5%) |
Chemotherapy setting, N (%) | ||||
1st line chemotherapy | 44 | (74.6%) | 378 | (79.6%) |
2nd line chemotherapy | 10 | (16.9%) | 68 | (14.3%) |
3rd line chemotherapy | 2 | (3.4%) | 13 | (2.7%) |
Preoperative adjuvant chemotherapy | 1 | (1.7%) | 14 | (2.9%) |
Postoperative adjuvant chemotherapy | 2 | (3.4%) | 2 | (0.4%) |
Time from start of first-line chemotherapy (days) | 71 | (35.5–253.5) | 220 | (112–386) |
Distant metastasis, N (%) | 43 | (72.9%) | 356 | (74.9%) |
Recurrent cancer, N (%) | 15 | (25.4%) | 155 | (32.6%) |