Skip to main content

Table 2 Clinical laboratory results in two patients who had taken single oral overdoses of diphenhydramine

From: Pharmacokinetic modeling of over-the-counter drug diphenhydramine self-administered in overdoses in Japanese patients admitted to hospital

  Time after administration of oral dose
Case 1 Case 2
2.5 h 11.5 h 3 h 18 h
Aspartate aminotransferase (U/L) 20 26 21 19
Alanine aminotransferase (U/L) 10 11 26 22
Total bilirubin (mg/dL) 1.6 1.5 0.5 0.6
Serum creatinine (mg/dL) 0.67 0.70 0.83 0.79
Creatinine clearance (mL/min) 109 104 108 113