Active TB infection and its associated factors among HIV-1 infected patients at Jimma medical center, Southwest Ethiopia

Table 4 Multivariate logistic regression analysis of factors associated with the development of active TB infection among HIV-1 infected patients at ART clinic of JMC

Variables		COR	Sig.	AOR	95 conf. Interval	Sig.
Education level	Illiterate	2.60	0.034	1.156	0.28–4.74	0.840
Education level	At least primary (reference)	1
Khat chewing	Yes	1.77	0.192	1.006	0.26–3.88	0.993
Khat chewing	No (reference)
Family history of TB	Yes	8.54	< 0.001	2.286	0.502–10.41	0.285
Family history of TB	No (Reference)	1
WHO clinical stage	III & IV	26.30	< 0.001	9.67	2.21–42.37	0.003
WHO clinical stage	I & II (reference)	1
CD4 cell count/μl	< 350	9.66	< 0.001	0.456	0.058–3.57	0.455
CD4 cell count/μl	> 350 (reference)	1
Functional status	Ambulatory and bed ridden	3.60	0.004	1.713	0.45–6.51	0.429
Functional status	Working (Reference)	1
Comorbidities	Yes	4.22	0.003	2.441	0.57–10.43	0.228
Comorbidities	No (Reference)	1
IPT	Yes	0.040	< 0.001	0.123	0.034–0.44	0.001
IPT	No (reference)	1
Cotrimoxazole prophylaxis	Yes	0.114	< 0.001	0.243	0.051–1.16	0.076
Cotrimoxazole prophylaxis	No (Reference)	1
ART adherence	Good	0.022	0.001	0.076	0.007–0.80	0.032
ART adherence	Poor (Reference)	1

Keys: IPT Isoniazid preventive therapy, ART Anti-retroviral therapy, C/AOR crude/adjusted odds ratio

ISSN: 2055-0294