Analysis of the variable factors affecting changes in the blood concentration of cyclosporine before and after transfusion of red blood cell concentrate

Table 3 Multiple regression analysis to identify factors associated with the variation in the CyA ratio

	Variable	no.	Partial regression coefficient	95% CI	Standardized partial regression coefficient	P
All cases	HCT ratio	381	0.389	0.153–0.624	0.162	< 0.01
All cases	Concomitant medication that could elevate Ca^a	381	0.279	0.129–0.428	0.183	< 0.001
Cases in which the CyA dose was not changed between before and after RCC transfusion	HCT ratio	165	0.479	0.166–0.792	0.227	< 0.01
	ΔALP	165	0.001	0.0001–0.001	0.168	0.027
	Concomitant medication that could elevate Ca^a	165	0.321	0.001–0.640	0.147	0.049

CI confidence interval, CyA cyclosporine, HCT hematocrit, Ca blood concentration of cyclosporine after RCC transfusion, ALP alkaline phosphatase. ^a No concomitant medication affecting Ca in Table 2 served as the reference group

ISSN: 2055-0294