Skip to main content

Table 1 Pharmacokinetic parameters of PSP in rats

From: Voriconazole injection may induce delayed methotrexate excretion: a case report and experimental study

 

2.5 mg/kg

25 mg/kg

 

control

SBECD

control

SBECD

ke (10−3 min−1)

ND

ND

10.2 ± 3.56

5.84 ± 1.63

CL (mL/min/kg)

ND

ND

9.71 ± 1.65

4.13 ± 0.76*

AUC (mmol·min/mL)

ND

ND

7.46 ± 1.32

10.9 ± 0.44*

  1. PSP was administered intravenously at 2.5 mg/kg or 25 mg/kg. SBECD was intravenously administered at 320 mg/kg. Each value represents the mean ± S.D. (n = 3). *p < 0.05
  2. ND: not determined due to quantitative limit
Back to article page

Journal of Pharmaceutical Health Care and Sciences

ISSN: 2055-0294

Contact us