Fig. 1From: Plasma and synovial fluid concentrations of linezolid in patients with knee osteoarthritis infected with Staphylococcus aureusClinical laboratory results and measured plasma concentrations of linezolid in two patients administered 600 mg twice daily by intravenous infusion. Levels of C-reactive protein (circles, mg/dL) and white blood cell counts (squares, μL− 1) in two patients are indicated: (A) a 69-year-old woman, case 1, and (B) a 73-year-old woman, case 2. Measured plasma concentrations of linezolid (closed circles) in case 1 (C) and case 2 (D) after administrations are shown. Also shown are the plasma concentrations of linezolid (dashed lines) after virtual daily doses generated using a previously reported one-compartment model [11]Back to article page