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Table 3 Multivariate logistic regression analysis of risk factors for AKI

From: Characteristics of risk factors for acute kidney injury among inpatients administered sulfamethoxazole/trimethoprim: a retrospective observational study

Independent variables

Univariate

Multivariate

OR

95% CI

p value

OR

95% CI

p value

Age, per year

1.03

1.00 − 1.06

0.02

   

Body mass index, per kg/m2

0.86

0.77 − 0.96

< 0.01

0.86

0.76 − 0.97

< 0.01

Hypertension (yes)

2.01

0.94 − 4.28

0.07

2.69

1.11 − 6.49

0.02

Treatment for infection (yes)

3.52

1.65 − 7.51

< 0.01

   

Daily dose, per SMX400 mg/TMP80 mg

1.13

1.02 − 1.25

0.02

1.16

1.03 − 1.30

0.02

Loop diuretics (yes)

3.97

1.74 − 9.08

< 0.01

2.91

1.08 − 7.78

0.04

β-lactams (yes)

2.32

1.10 − 4.88

0.03

   

Glycopeptides (yes)

8.48

1.64 − 43.99

0.02

6.24

0.89 − 43.98

0.07

Aminoglycosides (yes)

5.47

0.88 − 34.04

0.09

   
  1. We summarized the independent variables with < 0.10 in the univariate logistic regression analysis
  2. Of 281 patients, 32 had AKI and 249 did not have AKI
  3. AKI Acute kidney injury, OR Odds ratio, 95% CI 95% confidence interval, SMX Sulfamethoxazole, TMP Trimethoprim