Table 1 Patient characteristics (n = 67)

Sex (male/female)

37/30

Age (years)

62.5 ± 1.39

Anti-EGFR antibody drug

 Cetuximab

18

 Panitumumab

49

Regimen

 Cmab + FOLFIRI therapy

10

 Cmab + FOLFOX therapy

8

 Pmab + FOLFIRI therapy

26

 Pmab + FOLFOX therapy

23

Moisturizer

 Heparinoid

67

Supportive care drug

 Minocycline

37

Physical information

 Height (cm)

163.4 ± 0.99

 Body weight (kg)

60.4 ± 1.46

Blood biochemical data

 AST (IU/L)

29.2 ± 2.89

 ALT (IU/L)

23.3 ± 2.57

 T-Bil (mg/dL)

0.52 ± 0.04

 Scr (mg/dL)

0.77 ± 0.03