Fig. 2
Administration of NYT diet cancels intracellular Zn2+ level increased by Aβ1-42. Intracellular ZnAF-2 fluorescence was determined in the granule cell layer (GCL) of mice 1 h after ICV injection of Aβ1-42 (upper). Bar; 50 µm. The data (mean ± SEM) indicate the rate (%) of ZnAF-2 fluorescence after Aβ1-42 injection to that after saline (vehicle) injection that was indicated as 100% (lower). **, p < 0.01, vs. saline: #, p < 0.05, vs. Aβ (Tukey’s test). control/saline, 32 slices from 8 mice; control/Aβ, 29 slices from 8 mice; NYT/Aβ, 16 slices from 4 mice. Bar; 50 µm