Fig. 2From: A case report involving suppressed nuclear receptor transcription factors 4a1 and Stevens-Johnson syndrome induced by a single dose of pembrolizumab and successfully treated with early steroid administration, resulting in complete remission of stage III lung cancerComparisons of Nr4a1 mRNA expression levels. Individual levels were measured relative to the basal level in SJS cases. Levels in an SJS case (n = 9) were compared between two types of single non-SJS prednisolone-free controls, a nonresponding non-SJS progressive disease case (n = 6) and a responding non-SJS case for pembrolizumab (n = 17), using the Steel–Dwass test. Blood samples were drawn during hospitalization and after discharge and used for the evaluations. *p < 0.05, **P < 0.001Back to article page