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Fig. 2 | Journal of Pharmaceutical Health Care and Sciences

Fig. 2

From: A case report involving suppressed nuclear receptor transcription factors 4a1 and Stevens-Johnson syndrome induced by a single dose of pembrolizumab and successfully treated with early steroid administration, resulting in complete remission of stage III lung cancer

Fig. 2

Comparisons of Nr4a1 mRNA expression levels. Individual levels were measured relative to the basal level in SJS cases. Levels in an SJS case (n = 9) were compared between two types of single non-SJS prednisolone-free controls, a nonresponding non-SJS progressive disease case (n = 6) and a responding non-SJS case for pembrolizumab (n = 17), using the Steel–Dwass test. Blood samples were drawn during hospitalization and after discharge and used for the evaluations. *p < 0.05, **P < 0.001

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