Table 8 Baseline Patient’s Characteristics Stratified by Bleeding complications

 Age, years

71 (59–80)

77 (68–83)

0.164^a

 Male sex

8/5

50/39

0.773^c

 Body mass index

20.2 (18.1–21.8)

22.0 (19.2–25.5)

0.074^a

 Creatinine clearance, mL/min

14.1 (12.3–39.9)

22.3 (12.4–39.7)

0.479^a

 Renal replacement therapy

7 (53.8)

48 (53.9)

1.000^c

 Malignancy

3 (23.1)

19 (21.3)

1.000^c

 Serum albumin, mg/dL

2.40 (2.10–2.50)

2.30 (1.90–2.70)

0.687^a

 SOFA score

13 (9–14)

11 (9–14)

0.453^a

 JAAM-DIC score

6 (5–7)

6 (5–7)

0.723^a

 SIRS criteria

3 (3–4)

3 (2–4)

0.566^a

 Intra-abdominal infection

3 (23.1)

22 (24.7)

1.000^c

 Pneumonia

4 (30.8)

19 (21.3)

0.483^c

 Urinary tract infection

1 (7.7)

16 (18.0)

0.690^c

 Cholangitis/Cholecystitis

0 (0.0)

9 (10.1)

0.599^c

 Blood stream infection

0 (0.0)

7 (7.9)

0.591^c

 Infectious enteritis

2 (15.4)

0 (0.0)

0.015^c

 Necrotizing fasciitis/Gas gangrene

0 (0.0)

2 (2.2)

1.000^c

 Osteomyelitis

0 (0.0)

2 (2.2)

1.000^c

 Iliopsoas muscle abscess/Retroperitoneal abscess

0 (0.0)

2 (2.2)

1.000^c

 Unknown

3 (23.1)

6 (6.7)

0.087^c

 Dose reduction of TM

3 (23.1)

27 (30.3)

0.751^c

 Antithrombin III

11 (84.6)

67 (75.3)

0.728^c

 Heparin

0 (0.0)

3 (3.4)

1.000^c

 Fresh frozen plasma

6 (46.2)

23 (25.8)

0.186^c

 Platelet Concentrate

6 (46.2)

31 (34.8)

0.539^c

 PMX-DHP

5 (38.5)

43 (48.3)

0.564^c