Fig. 4

Observed versus predicted AUC_0-12 of MPA. The straight line represents the identity line. The outer dot line indicates the limit of confidence interval, and the inside dot line indicates the limit of credible interval. MAP-BE, maximum a posteriori Bayesian estimation; MLR, multiple linear regression; AUC_observed, AUC_0-12 calculated from MPA concentrations at the 9 time points of C₀ to C₁₂, using the linear trapezoidal method; AUC_predicted, the predicted value of AUC_0-12