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Table 1 Demographic characteristics of patients (n = 34)

From: Population pharmacokinetics and limited sampling strategy for therapeutic drug monitoring of mycophenolate mofetil in Japanese patients with lupus nephritis

Patient characteristics

Median (IQR) or number

Sex

 Male

6

 

 Female

28

 

 Age (years)

39.0

(26.3–51.8)

 Body weight (kg)

54.7

(47.2–58.6)

 Serum albumin (g/dL)

3.6

(2.8–3.9)

 Serum creatinine (mg/dL)

0.66

(0.54–0.79)

 Estimated GFR (mL/min)

77.4

(60.3–93.1)

 Creatinine clearance (mL/min)

103.6

(71.1–125.0)

 Urine protein/creatinine ratio (g/gCre)

0.25

(0.14–1.62)

 Alanine aminotransferase (U/L)

16.0

(13.0–20.0)

 Aspartate aminotransferase (U/L)

17.0

(13.3–22.0)

 Total bilirubin (mg/dL)

0.56

(0.43–0.66)

 C-reactive protein (mg/dL)

0.06

(0.04–0.15)

 Dose of MMF (mg/day)

1500

(1500–1688)

 Dose of MMF/body weight (mg/day/kg)

27.9

(24.1–33.2)

No. of patients receiving concomitant drugs

 Prednisolone

34

 

 Dose of prednisolone (mg)

10

(8–30)

 Tacrolimus

8

 

 Proton pump inhibitor

22

 

 Iron/magnesium oxide

5

 

 NSAIDs

3

 
  1. IQR interquartile range, GFR glomerular filtration rate, NSAIDs nonsteroidal anti-inflammatory drugs