Table 3 Factors influencing the plasma bepridil concentration ≥800 ng/mL in patients with HF on multivariate logistic analysis
Factors | Adjusted OR | 95% CI | p value |
|---|---|---|---|
Age ≥70 years | 1.90 | 0.571–6.321 | 0.295 |
Daily dose of bepridil ≥1.6 mg/kg body weight | 6.82 | 2.104–22.132 | 0.001 |
Polypharmacy | 2.96 | 1.014–8.643 | 0.047 |
Concomitant of aprindine | 8.63 | 1.684–44.215 | 0.010 |
Ccr ≤30 mL/min | 2.75 | 0.848–8.927 | 0.092 |
LVEF ≤50% | 1.76 | 0.578–5.358 | 0.320 |