Table 3 Residual percentages of (±)-tramadol in aqueous solution in a clinical setting at day 14
From: Photostability studies on (±)-tramadol in a liquid formulation
(A) Comparison of dispensing bottles and light conditions | |||||||||
|---|---|---|---|---|---|---|---|---|---|
Residual percentages (C/C 0, %) | |||||||||
( n ) | NDBs | LSDBs | P -value | ||||||
(±)-tramadol (Sunlight) | (5) | 94.6 ± 3.1 | P =0.29 | 99.9 ± 2.8 | P =0.90 | 0.20 | |||
(±)-tramadol (Diffused light) | (5) | 103.4 ± 15.9 | 100.9 ± 15.3 | 0.82 | |||||
B) Comparison of (+)-tramadol and (−)-tramadol | |||||||||
Residual percentages (C/C 0, %) | |||||||||
Sunlight | Diffused light | ||||||||
( n ) | NDBs | LSDBs | NDBs | LSDBs | |||||
(+)-tramadol | (5) | 94.6 ± 3.4 | P =0.97 | 100.2 ± 3.4 | P =0.75 | 104.3 ± 15.6 | P =0.86 | 102.6 ± 14.4 | P =0.75 |
(−)-tramadol | (5) | 94.7 ± 2.4 | 99.6 ± 1.7 | 102.4 ± 14.5 | 99.2 ± 14.4 | ||||