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Table 1 CDDP administration regimen by the short hydration

From: Feasibility study of short hydration using oral rehydration solution in cisplatin including chemotherapy of lung cancer

Rp

Drugs

Volume

Infusion time

1

ORS

1000 mL

Oral intake

2

Aprepitant (125 mg)

 

Oral intake

3

Palonosetron (0.75 mg) Dexamethasone (9.9 mg) diluted with Saline

100 mL

30 min

4

Maintenance solution mixed MgSO4 (8 mEq)

500 mL

60 min

5

VP-16, CPT-11, GEM, DTX, PEM diluted with Saline or 5%Glusosea

100 ~ 500 mL

10 ~ 90 min

6

Cisplatin 60 ~ 80 mg/m2 diluted with Saline

500 mL

120 min

7

Flosemide (20 mg) diluted with Saline

50 mL

5 min

8

Mentenance solution mixed MgSO4 (8 mEq)

500 mL

60 min

  1. a VP-16 (100 mg/m2)diluted with saline 500 mL; 90 min, CPT-11 (60 mg/m2) diluted with saline 500 mL; 90 min
  2. GEM (1000 mg/m2) diluted with 5%glucose; 30 min, DTX (60 mg/m2) diluted with saline 250 mL; 60 min
  3. PEM (500 mg/m2) diluted with saline 100 mL; 10 min