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Table 1 Profiles of the patients included in the case-control study

From: Predictors of the therapeutic effect of sivelestat in patients with acute lung injury associated with systemic inflammatory response syndrome

 

Effective group (n = 28)

Ineffective group (n = 25)

P

Age(yr)

67.7 ± 14.5

77.0 ± 8.4

0.006 b

Male (%)

21 (75.0 %)

20 (80.0 %)

0.664 c

Sepsis (%)

8 (28.6 %)

13 (52.0 %)

0.082 c

DIC (%)

9 (32.1 %)

11 (44.0 %)

0.374 c

ALT(IU/L)

46.8 ± 38.9

29.3 ± 26.4

0.064 a

AST(IU/L)

67.3 ± 61.9

75.1 ± 119.1

0.772 b

LDH(IU/L)

569 ± 222

670 ± 744

0.350 b

ALP(IU/L)

306 ± 160

500 ± 829

0.315 b

γ-GTP(IU/L)

68.9 ± 80.2

40.2 ± 34.6

0.121 b

BUN(mg/dL)

31.9 ± 20.8

37.3 ± 21.6

0.353 a

Scr(mg/dL)

2.0 ± 2.7

2.1 ± 2.6

0.961 a

RBC(×104/μL)

376.1 ± 84.9

327.2 ± 72.1

0.029 a

WBC(/μL)

11,121 ± 7299

13,441 ± 8549

0.292 a

Neut(%)

88.4 ± 9.3

85.9 ± 10.3

0.607 a

Plt(×104/μL)

18.8 ± 9.8

16.0 ± 9.8

0.295 a

Alb(g/dL)

3.1 ± 2.0

2.4 ± 0.6

0.127 b

CRP(mg/dL)

19.6 ± 11.2

15.5 ± 9.4

0.168 a

[H+](×10−8)

3.639 ± 0.667

4.422 ± 0.936

0.001 b

PO2(mmHg)

93.2 ± 48.1

61.4 ± 24.7

0.004 b

PCO2(mmHg)

36.6 ± 9.3

47.7 ± 17.5

0.007 b

Dose(mg/kg/h)

0.216 ± 0.049

0.209 ± 0.046

0.785 a

  1. The data were expressed as the mean ± standard deviation, except for the number of males, sepsis, and DIC. The value of [H+] was calculated as follows: [H+] = 10–pH
  2. a: Student t-test, b: Welch’s t-test, c: Chi-square test
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Journal of Pharmaceutical Health Care and Sciences

ISSN: 2055-0294

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