Table 2 Characteristics of patients with or without renal dysfunction

Age (years) ^a

45.0 (38.0–52.0)

29.5 (24.0–35.8)

Body weight (kg) ^a

52.2 (49.4–62.9)

60.8 (59.0–68.8)

BMI (kg/m²) ^a

17.7 (17.2–20.9)

21.3 (20.2–23.8)

BSA (m²) ^a

1.60 (1.57–1.77)

1.70 (1.69–1.79)

Serum creatinine (mg/dL) ^a

0.70 (0.65–0.80)

0.80 (0.78–0.83)

eGFR (mL/min · 1.73 m²) ^a

96.1 (85.9–102.9)

90.4 (82.7–104.2)

Rate of decrease in eGFR (%) ^a

33.2 (24.3–38.2)

11.7 (8.0–12.9)

CD4⁺ cell count (/μL) ^a

58 (36–133)

204 (99–320)

HIV RNA viral load (log₁₀/mL) ^a

4.63 (4.52–5.84)

5.33 (4.82–5.92)

Protease inhibitors (ritonavir-boosted), n (%)

4 (57.1)

3 (75.0)

INSTIs, n (%)

3 (42.9)

1 (25.0)

Concurrent use of a nephrotoxic drug, n (%)

2 (28.6)

2 (50)

Hepatitis B, n (%)

3 (42.6)

0 (0)

Plasma TFV concentration (ng/mL) ^a

88.0 (67.0–102.5)

56.0 (50.5–60.5)