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Table 1 Antineoplastic agents used in this study

From: Evaluation of the permeation of antineoplastic agents through medical gloves of varying materials and thickness and with varying surface treatments

Antineoplastic agents

Brand name

Concentration [mg/mL]

MWa

logPb

Etoposide

Lastet® Inj. 100 mg/5 mL

(Nippon Kayaku Co., Ltd)

20

588.6

0.6 [13]

Cyclophosphamide monohydrate

Endoxan® 100 mg

(Shionogi & Co., Ltd)

20

261.1c

0.6 [13]

Doxorubicin hydrochloride

ADRIACIN® Injection 10

(Kyowa Hakko Kirin Co., Ltd)

10

543.5d

1.4 [14]

Paclitaxel

TAXOL® INJECTION 30 mg

(Bristol-Myers Squibb)

6

853.9

3.7 [15]

Fluorouracil

5-FU Injection 250 Kyowa®

(Kyowa Hakko Kirin Co., Ltd.)

50

130.8

−1.0 [16]

  1. amolecular weight
  2. blogarithm of Partition coefficient
  3. cas anhydride
  4. das free base