Table 2 Patient and microbiological characteristics

Sex (men: women)

27:18

8:4

19:14

0.74 ⁱ⁾

Age (years) ^a

73 (64–83)

71 (63–79)

75 (63–84)

0.38 ⁱⁱ⁾

Height (cm)^a

158.0 (151.8–166.0)

159.2 (153.5–169.4)

156.7 (150.3–165.3)

0.24 ⁱⁱ⁾

Body weight (kg)^a

51.0 (42.8–56.9)

56.5 (48.6–68.6)

48.8 (41.5–54.7)

0.012 ⁱⁱ⁾

Number of ICU admissions

12 (26.7%)

3 (25%)

9 (27.3%)

0.11 ⁱ⁾

ID specialist interventions

27 (60.0%)

6 (50.0%)

21 (63.6%)

0.50 ⁱ⁾

Monotherapy

(number of patients)

45

12

33

1.00 ⁱ⁾

ALT (IU/L) ^a

30 (16–55)

25 (13–44)

33 (16–64)

0.29 ⁱⁱ⁾

ALP (IU/L, N = 40)^a

544 (302–1245)

557 (306–822, N = 10)

545 (286–1467, N = 30)

0.53 ⁱⁱ⁾

T–Bil (mg/dL)^a

0.9 (0.5–3.1)

1.0 (0.5–2.8)

0.8 (0.5–3.3)

0.63 ⁱⁱ⁾

WBC (×  10³/μL) ^a

8.5 (4.9–12.3)

12.5 (7.0–23.8)

7.4 (4.8–11.3)

0.047 ⁱⁱ⁾

PLT (× 10³/μL)^a

176.0 (101.5–269.5)

101.5 (86.0–15)

237.0 (127.0–303.0)

0.0056 ⁱⁱ⁾

SCr (mg/dL)^a

0.81 (0.66–1.00)

0.79 (0.65–0.96)

0.83 (0.66–1.01)

0.75 ⁱⁱ⁾

eGFR (mL/min/1.73 m²)^a

67.0 (52.0–78.0)

71.0 (51.3–78.0)

66.0 (52.0–77.0)

0.69 ⁱⁱ⁾

CLcr (mL/min)^ab

53.6 (39.4–78.1)

61.7 (51.4–89.1)

48.9 (36.7–73.4)

0.10 ⁱⁱ⁾

ARC risk score^a

1 (1–1)

1 (0–1)

1 (1–1)

0.09 ⁱⁱ⁾

Acute kidney injury patients^c

11 (24.4%)

5 (41.7%)

6 (18.2%)

0.11 ⁱ⁾

CCI^a

4(2–6)

6 (5–7)

3 (2–6)

0.0081 ⁱⁱ⁾

SOFA score (a)^a

2 (0–4)

3 (1–6)

2 (0–3)

0.060 ⁱⁱ⁾

SOFA score (b)^a

2 (0–5)

6 (4–8)

2 (0–2)

< 0.0001 ⁱⁱ⁾

SOFA score (b)-(a)^a

0 (0–1)

3 (0–3)

0 (−1–0)

< 0.0001 ⁱⁱ⁾

 Catheter-related infection

4

3

1

N.A

 Biliary tract infection

22

5

17

 Urinary tract infection

5

2

3

 Intra–abdominal infection

5

0

5

 Unknown

9

2

7

  ≤ 0.5 μg/mL

14

4 (33.3%)

10 (30.3%)

NA

 1.0 μg/mL

29

7 (58.3%)

22 (66.7%)

 2.0 μg/mL

1

0

1 (3.0%)

 4.0 μg/mL

1

1 (8.3%)

0

Positive polymicrobial blood culture

15

3

12

0.72 ⁱ⁾