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Table 3 Characteristics of patients in the AKI group and the non-AKI group

From: Higher incidence of acute kidney injury in patients treated with piperacillin/tazobactam than in patients treated with cefepime: a single-center retrospective cohort study

Parameters

AKI group

( n = 15)

Non-AKI group

( n = 251)

p-value

PIPC/TAZ, n (%)

14 (93.3)

149 (59.4)

0.011

Age, median (range)

80 (59 – 96)

75 (21 – 95)

0.31

Female, n (%)

6 (40.0)

79 (31.5)

0.57

Hypertension, n (%)

8 (53.3)

122 (48.6)

0.79

Heart failure, n (%)

5 (33.3)

34 (13.5)

0.051

Diabetes, n (%)

9 (60.0)

59 (23.5)

0.006

Malignancy, n (%)

7 (46.7)

86 (34.3)

0.40

Prostatic hypertrophy, n (%)

4 (26.7)

45 (17.9)

0.49

CKD, n (%)

12 (80.0)

95 (37.8)

0.0019

Contrast media, n (%)

2 (13.3)

27 (10.8)

0.67

NSAIDs, n (%)

5 (33.3)

124 (49.4)

0.29

ACE-I / ARB, n (%)

6 (40.0)

73 (29.1)

0.39

Diuretics, n (%)

7 (46.7)

59 (23.5)

0.062

Calcineurin inhibitors, n (%)

0 (0)

2 (0.8)

1

Catecholamine, n (%)

2 (13.3)

8 (3.2)

0.10

Aminoglycoside, n (%)

0 (0)

2 (0.8)

1

Acyclovir, n (%)

0 (0)

1 (0.4)

1

Cisplatin, n (%)

0 (0)

1 (0.4)

1

  1. PIPC/TAZ Piperacillin/tazobactam, CKD Chronic kidney disease, NSAIDs Non-steroidal anti-inflammatory drugs, ACE-I Angiotensin-converting enzyme inhibitors, ARB Angiotensin-II receptor blockers