Fig. 1

Permeation rates (PRs) of the 10 antineoplastic agents through nitrile gloves of varying thicknesses. The PRs of the 10 antineoplastic agents through nitrile medical gloves are shown. a-j correspond to carboplatin (CBDCA), carmustine (BCNU), cisplatin (CDDP), cyclophosphamide (CPA), doxorubicin (DXR), etoposide (ETP), fluorouracil (5FU), ifosfamide (IFM), oxaliplatin (OXA), and paclitaxel (PTX), respectively. The symbols and bars indicate mean and standard deviation (SD), respectively (n = 3). Open circles, open squares, and open triangles indicate the data obtained using nitrile gloves of 0.05, 0.07, and 0.1 mm thicknesses, respectively. The dotted line indicates the PR upper limit (10 ng/min/cm²) determined based on the American Society of Testing and Materials D6978–05 guidelines. Throughout the permeation experiment, CDDP, DXR, and OXA were not detected in the receptor solution