Fig. 4

Appearances of crushed fluoroquinolone film-coated tablets mixed with 1.5% (w/v) XG-FTs. a LVFX film-coated tablets immersed in 1.5% (w/v) XG-FTs, b LVFX crushed film-coated tablets immersed in 1.5% (w/v) XG-FTs, c TFLX film-coated tablets immersed in 1.5% (w/v) XG-FTs, d TFLX crushed film-coated tablets immersed in 1.5% (w/v) XG-FTs, e CPFX film-coated tablets immersed in 1.5% (w/v) XG-FTs, f CPFX crushed film-coated tablets immersed in 1.5% (w/v) XG-FTs. CPFX film-coated tablets did not disintegrate owing to the gel layer formed on the surface (e). However, crushed CPFX film-coated tablets separated into a liquid and a translucent gel (f). Crushed LVFX and TFLX film-coated tablets were non-uniformly dispersed following XG-FT addition (a, b, c, d)