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Table 1 Top 11 substances causing acute poisoning from overdoses that led to admission to the emergency room of Kyoto Medical Center

From: Pharmacokinetic modeling of over-the-counter drug diphenhydramine self-administered in overdoses in Japanese patients admitted to hospital

Substance Number of poisoning cases (%)
1. Flunitrazepama 12 (7.8)
2. Diphenhydramine 8 (5.2)
3. Etizolam a 7 (4.5)
4. Quetiapine 7 (4.5)
5. Ethanol 6 (3.9)
6. Lorazepama 5 (3.2)
7. Triazolama 5 (3.2)
8. Brotizolama 4 (2.6)
9. Diazepama 4 (2.6)
10. Loxoprofen 4 (2.6)
11. Risperidonea 4 (2.6)
Total 154 (100)
  1. We conducted a cohort study of 87 patients who self-administered substances that resulted in acute poisoning and admission to the emergency room of Kyoto Medical Center between January 2018 and March 2021
  2. aThese seven substances are reported to be commonly ingested in cases of deliberate drug poisoning in Japan [3]