Table 1 Demographic data and clinical characteristics of COPD patients

Gender

female

16 (61.54%)

20 (39.22%)

13 (56.52%)

0.128

male

10 (38.46%)

31 (60.78%)

10 (43.48%)

Age

30–50

2 (7.69%)

6 (11.76%)

7 (30.43%)

0.096

51–70

16 (61.54%)

35 (68.63%)

15 (65.22%)

71–90

8 (30.77%)

9 (17.65%)

1 (4.35%)

> = 91

0 (0%)

1 (1.96%)

0 (0%)

BMI

thin

3 (11.54%)

12 (23.53%)

1 (4.35%)

0.172

normal

10 (38.46%)

18 (35.29%)

11 (47.83%)

overweight

9 (34.62%)

10 (19.61%)

9 (39.13%)

obese

4 (15.38%)

11 (21.57%)

2 (8.7%)

Education Level

>12th grade of high school

20 (76.92%)

24 (47.06%)

8 (34.78%)

0.008

≤12th grade of high school

6 (23.08%)

27 (52.94%)

15 (65.22%)

Comorbidities

 Diabetes

no

23 (88.46%)

46 (90.2%)

20 (86.96%)

0.914

yes

3 (11.54%)

5 (9.8%)

3 (13.04%)

 Ischemic Heart Disease

no

24 (92.31%)

42 (82.35%)

23 (100%)

0.066

yes

2 (7.69%)

9 (17.65%)

0 (0%)

 High Cholesterol

no

22 (84.62%)

38 (74.51%)

20 (86.96%)

0.367

yes

4 (15.38%)

13 (25.49%)

3 (13.04%)

 Hypertension

no

14 (53.85%)

30 (58.82%)

18 (78.26%)

0.171

yes

12 (46.15%)

21 (41.18%)

5 (21.74%)

Polypharmacy

no

3 (11.54%)

20 (39.22%)

19 (82.61%)

< 0.001

yes

23 (88.46%)

31 (60.78%)

4 (17.39%)

Current-smoking status

no

26 (100%)

48 (94.12%)

22 (95.65%)

0.458

yes

0 (0%)

3 (5.88%)

1 (4.35%)

Influenza vaccine

no

14 (53.85%)

26 (50.98%)

10 (43.48%)

0.754

yes

12 (46.15%)

25 (49.02%)

13 (56.52%)

Pneumococcal vaccine

no

26 (100%)

50 (98.04%)

22 (95.65%)

0.555

yes

0 (0%)

1 (1.96%)

1 (4.35%)

SGRQ-C

Low quality

≥ 25

26 (100%)

50 (98.04%)

5 (21.74%)

< 0.001

High quality<  25

0 (0%)

1 (1.96%)

18 (78.26%)

Mean (SD)

81.34 (7.82)

49.76 (14.15)

18.26 (8.29)

< 0.001

CAT

Low health status

≥ 10

26 (100%)

38 (74.51%)

1 (4.35%)

< 0.001

High health status

<  10

0 (0%)

13 (25.49%)

22 (95.65%)

Mean (SD)

27.04 (6.2)

15.25 (6.79)

5.35 (2.77)

< 0.001

mMRC

High level of breathlessness

≥ 2

26 (100%)

51 (100%)

12 (52.17%)

< 0.001

Low level of breathlessness

<  2

0 (0%)

0 (0%)

11 (47.83%)

Median (25–75 percentile)

4 (3–4)

2 (1–2)

1 (0–1)

< 0.001

FEV1(%) mean(±SD)

39.5(±14.45)

49.65(±17.16)

59.78(±12.31)

< 0.001

Number of administered drugs

Median (25–75 percentile)

6 (5–8)

6 (4–8)

3 (2–4)

< 0.001

Disease Duration (years)

Median (25–75 percentile)

9 (4–17)

4 (1–10)

4 (1–8)

0.04