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Table 2 Clinical course of a 92-year-old female patient diagnosed with complete atrioventricular block

From: A case of complete atrioventricular block with extremely high blood concentration of azelnidipine

Time

Event

For more than 10 years before admission

Use of azelnidipine 16 mg/day and simvastatin 5 mg/day

Day 1

Patient complained of dyspnea and palpitations.

Patient was prescribed furosemide, spironolactone and cibenzoline.

Day 4

Patient was diagnosed with complete atrioventricular block (CAVB) and hospitalized.

Oral administration of furosemide, spironolactone and cibenzoline was discontinued.

Intravenous administration of furosemide was started.

Temporary pacemaker was implanted.

Day 7

Patient returned to a normal sinus rhythm, and the symptoms of dyspnea resolved.

Intravenous administration of furosemide was discontinued.

Temporary pacemaker was removed.

Day 13

Patient was discharged.

Day 34

Patient was again diagnosed with CAVB.

Oral administration of azelnidipine and simvastatin was discontinued.

Day 41

Electrocardiogram (ECG) confirmed an episode of CAVB.

No subjective symptoms were observed.

Day 71

ECG showed no episode of CAVB.

Over the course of the next 5 months

ECG was performed once a month, with no evidence of CAVB.