From: A case of complete atrioventricular block with extremely high blood concentration of azelnidipine
Time | Event |
---|---|
For more than 10 years before admission | Use of azelnidipine 16 mg/day and simvastatin 5 mg/day |
Day 1 | Patient complained of dyspnea and palpitations. |
Patient was prescribed furosemide, spironolactone and cibenzoline. | |
Day 4 | Patient was diagnosed with complete atrioventricular block (CAVB) and hospitalized. |
Oral administration of furosemide, spironolactone and cibenzoline was discontinued. | |
Intravenous administration of furosemide was started. | |
Temporary pacemaker was implanted. | |
Day 7 | Patient returned to a normal sinus rhythm, and the symptoms of dyspnea resolved. |
Intravenous administration of furosemide was discontinued. | |
Temporary pacemaker was removed. | |
Day 13 | Patient was discharged. |
Day 34 | Patient was again diagnosed with CAVB. |
Oral administration of azelnidipine and simvastatin was discontinued. | |
Day 41 | Electrocardiogram (ECG) confirmed an episode of CAVB. |
No subjective symptoms were observed. | |
Day 71 | ECG showed no episode of CAVB. |
Over the course of the next 5 months | ECG was performed once a month, with no evidence of CAVB. |