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Table 2 Logistic regression analysis for factors influencing temperature increase more than 1.0 C 24-h post-infusion of casirivimab-imdevimab

From: Casirivimab-imdevimab neutralizing SARS-CoV-2: post-infusion clinical events and their risk factors

  

Univariate Analysis

Multivariate Analysis

Factor

Cutoff

OR

CI, lower

CI, upper

P

OR

CI, lower

CI, upper

P

Age

55

1.8

0.802

4.042

0.154

    

Male

 

1.977

0.876

4.463

0.101

    

Smoking

 

1.020

0.448

2.322

0.962

    

Body Mass Index

23

2.166

0.955

4.913

0.064

    

Symptomatic

3 days

0.976

0.425

2.241

0.954

    

CT Bilateral

 

2.237

0.95

5.265

0.065

    

PreTemp

37

0.695

0.307

1.578

0.385

    

PreOx

96%

1.646

0.434

6.250

0.464

    

White Blood Cell

4.3 × 103

2.412

1.050

5.537

0.038*

2.593

1.060

6.338

0.037*

Neutrophil

64%

1.415

0.631

3.174

0.400

    

Lymphocyte

24%

0.778

0.349

1.736

0.540

    

C-Reactive Protein

0.53 mg/dl

0.852

0.381

1.907

0.697

    

Total Bilirubin

0.55 mg/dl

4.390

0.881

21.881

0.071

    

Creatinine

0.7 mg/dl

2.912

1.157

7.331

0.023*

2.217

0.822

5.981

0.116

Platelet

180 × 103

1.095

0.490

2.446

0.824

    

2-Time Vaccination

 

0.123

0.026

0.581

0.008*

0.125

0.025

0.623

0.011*

  1. CI, 95% confidence interval; CT Bilateral, computed tomography showing bilateral ground glass attenuation; PreTemp, pre-infusion body temperature; PreOx, pre-infusion pulse oximetry; *, P < 0.05
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Journal of Pharmaceutical Health Care and Sciences

ISSN: 2055-0294

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