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Table 1 Values of AUCallopurinol, AUCoxypurinol, and AUCtotal in Crl:CD and Jcl:SD rats. Rats were administered allopurinol 30 or 100 mg/kg with or without febuxostat (10 mg/kg). AUCtotal is the sum of AUCallopurinol and AUCoxypurinol. Each bar represents the mean ± S.D. of 3 experiments

From: Xanthine oxidase and aldehyde oxidase contribute to allopurinol metabolism in rats

  1. Means±S. D. (mmol・h/L)