Table 3 Baseline Patient’s Characteristics Stratified by DIC resolution

Patient characteristics

 Age, years

76 (66–84)

78 (69–83)

0.392^a

 Male sex

23 (41.8)

35 (74.5)

0.002^b

 Body mass index

21.7 (19.2–25.7)

21.7 (18.8–24.4)

0.582^a

 Creatinine clearance, mL/min

26.5 (13.1–49.1)

15.6 (11.8–31.0)

0.046^a

 Renal replacement therapy

24 (43.6)

31 (66.0)

0.040^b

 Malignancy

10 (18.2)

13 (25.5)

0.510^b

 Serum albumin, mg/dL

2.4 (2.0–2.8)

2.3 (2.0–2.7)

0.294^a

Illness severity

 SOFA score

9 (8–12)

13 (10–16)

< 0.001^a

 JAAM-DIC score

5 (5–7)

6 (5–8)

0.053^a

 SIRS criteria

3 (2–4)

3 (3–4)

0.199^a

Primary type of Infection

 Intra-abdominal infection

16 (29.1)

9 (19.1)

0.260^c

 Pneumonia

6 (10.9)

17 (36.2)

0.004^c

 Urinary tract infection

11 (20.0)

6 (12.8)

0.427^c

 Cholangitis/Cholecystitis

9 (16.4)

0 (0.0)

0.003^c

 Blood stream infection

3 (5.5)

4 (8.5)

0.701^c

 Infectious enteritis

2 (3.6)

0 (0.0)

0.498^c

 Necrotizing fasciitis/Gas gangrene

1 (1.8)

1 (2.1)

1.000^c

 Osteomyelitis

2 (3.6)

0 (0.0)

0.498^c

 Iliopsoas muscle abscess/Retroperitoneal abscess

1 (1.8)

1 (2.1)

1.000^c

 Unknown

2 (3.6)

7 (14.9)

0.077^c

Treatment

 Dose reduction of TM alfa

9 (16.4)

21 (44.7)

0.002^c

 Antithrombin III

40 (72.7)

38 (80.9)

0.360^c

 Heparin

1 (1.8)

2 (4.3)

0.594^c

 Fresh frozen plasma

18 (38.3)

11 (20.0)

0.049^b

 Platelet Concentrate

15 (27.3)

22 (46.8)

0.066^b

 PMX-DHP

28 (50.9)

20 (42.6)

0.520^b