All-cause mortality at 30 days | |||
---|---|---|---|
Yes (N = 30) | No (N = 72) | p value | |
Patient characteristics | |||
Age, years | 74 (69–80) | 77 (67–84) | 0.683a |
Male sex | 21 (70.0) | 37 (51.4) | 0.124c |
Body mass index | 21.4 (17.0–24.2) | 21.7 (19.2–25.5) | 0.352a |
Creatinine clearance, mL/min | 21.3 (12.7–29.4) | 20.6 (12.4–42.6) | 0.523a |
Renal replacement therapy | 20 (66.7) | 35 (48.6) | 0.147b |
Malignancy | 8 (26.7) | 14 (19.4) | 0.437c |
Serum albumin, mg/dL | 2.15 (1.90–2.50) | 2.45 (2.08–2.73) | 0.093a |
Illness severity | |||
SOFA score | 15 (12–17) | 10 (8–12) | < 0.001a |
JAAM-DIC score | 6 (5–7) | 6 (5–7) | 0.448a |
SIRS criteria | 3 (2–4) | 3 (2–4) | 0.832a |
Primary type of Infection | |||
Intra-abdominal infection | 4 (13.3) | 21 (29.2) | 0.129c |
Pneumonia | 14 (46.7) | 9 (12.5) | < 0.001c |
Urinary tract infection | 2 (6.7) | 15 (20.8) | 0.142c |
Cholangitis/Cholecystitis | 0 (0.0) | 9 (12.5) | 0.055c |
Blood stream infection | 3 (10.0) | 4 (5.6) | 0.417c |
Infectious enteritis | 0 (0.0) | 2 (2.8) | 1.000c |
Necrotizing fasciitis/Gas gangrene | 0 (0.0) | 2 (2.8) | 1.000c |
Osteomyelitis | 1 (3.3) | 1 (1.4) | 0.504c |
Iliopsoas muscle abscess/Retroperitoneal abscess | 0 (0.0) | 2 (2.8) | 1.000c |
Unknown | 5 (16.7) | 4 (5.6) | 0.119c |
Treatment | |||
Dose reduction of TM | 14 (46.7) | 16 (22.2) | 0.026b |
Antithrombin III | 26 (86.7) | 52 (72.2) | 0.133c |
Heparin | 1 (3.3) | 2 (2.8) | 1.000c |
Fresh frozen plasma | 11 (36.7) | 18 (25.0) | 0.342b |
Platelet Concentrate | 12 (40.0) | 25 (34.7) | 0.780b |
PMX-DHP | 8 (26.7) | 40 (55.6) | 0.009c |