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Table 1 Pharmacokinetic analysis of in vitro penetration of FEL gel into rat skin

From: Skin absorption of felbinac solid nanoparticles in gel formulation containing l-menthol and carboxypolymethylene

Gel

J c

(×10− 2 µmol/cm2/h)

K p

(×10− 3 cm/h)

K m

(×10− 4)

τ

(h)

D

(×10− 3 cm2/h)

FEL-MP gel

0.11 ± 0.004

0.03 ± 0.001

20 ± 0.03

0.96 ± 0.03

0.87 ± 0.03

FEL-NP gel

0.21 ± 0.015*

0.06 ± 0.004*

53 ± 0.39*

1.08 ± 0.15

0.77 ± 0.14

  1. n = 8. * P < 0.05, vs. FEL-MP gel for each category
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Journal of Pharmaceutical Health Care and Sciences

ISSN: 2055-0294

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