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  1. Infusion-related reactions (IRRs) are major side effects of rituximab administration. Male sex, high body weight, body surface area (BSA), and body mass index are predictive markers of rituximab-induced IRRs. ...

    Authors: Hironobu Nishiura, Masaya Takahashi, Katsuhito Mori, Takashi Sugimoto, Masanori Emoto and Yasutaka Nakamura
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:12
    Content type: Short report Published on:

  2. We evaluated the predictive factors for surgical site infections (SSIs) in elective colorectal cancer surgery and the role of antimicrobial stewardship (AS) pharmacists in modifying the clinical pathway.

    Authors: Yasuhiro Sasaki, Akira Kurishima, Chieko Miyamoto, Kenichiro Hataji, Toru Tezuka and Hideo Katsuragawa
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:11
    Content type: Short report Published on:

  3. Pembrolizumab can cause immune-related adverse events such as adrenal insufficiency (AI). However, there is no consensus regarding appropriate monitoring of adrenal function during subsequent chemotherapy in p...

    Authors: Tatsuhiro Fujimiya, Kanako Azuma, Yuki Togashi, Koji Kuwata, Sakae Unezaki and Hironori Takeuchi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:10
    Content type: Case report Published on:

  4. Hospital pharmacists are important in antibiotic stewardship programs (ASP), a global strategy to combat antibiotic resistance (ABR). South African public hospitals have limited ASP implementation. This study ...

    Authors: Tiyani Comfort Mthombeni, Johanita Riétte Burger, Martha Susanna Lubbe and Marlene Julyan
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:9
    Content type: Research article Published on:

  5. Corticosteroid-containing medications are widely accessible in various forms, including topical, injectable, and inhaled formulations. Due to uncertain safety profiles, healthcare providers, including pharmaci...

    Authors: Muna Barakat, Samar Thiab, Rana Abu Farha, Anas O. Alshweiki, Roa’a Thaher, Asem Alsughaier and Diana Malaeb
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:8
    Content type: Research article Published on:

  6. Multidrug-resistant bacterial strains cause several serious infections that can be fatal, such as Enterococcus faecium, Staphylococcus aureus, Klebsiella pneumonia, Acinetobacter baumannii, Pseudomonas aeruginosa

    Authors: Showkat Ahmad Bhat, Mohammed Iqbal Zargar, Shahid Ud Din Wani, Ishfaq Mohiuddin, Mubashir Hussain Masoodi, Faiyaz Shakeel, Mohammad Ali and Seema Mehdi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:7
    Content type: Research article Published on:

  7. Hospitals in Japan established the healthcare delivery system from FY 2018 to 2021 by acquiring an additional reimbursement for infection prevention (ARIP) of category 1 or 2. However, research on outcomes of ...

    Authors: Yuichi Tasaka, Takeshi Uchikura, Shiro Hatakeyama, Daisuke Kikuchi, Masami Tsuchiya, Ryohkan Funakoshi and Taku Obara
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:6
    Content type: Research article Published on:

  8. Therapeutic drug monitoring (TDM) systems generally use either liquid chromatography/tandem mass spectrometry (LC-MS/MS) or immunoassay, though both methodologies have disadvantages. In this study, we aimed to...

    Authors: Tsutomu Shimada, Daisuke Kawakami, Arimi Fujita, Rintaro Yamamoto, Satoshi Hara, Kiyoaki Ito, Ichiro Mizushima, Shinji Kitajima, Yasunori Iwata, Norihiko Sakai, Mitsuhiro Kawano, Takashi Wada and Yoshimichi Sai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:5
    Content type: Research article Published on:

  9. As methadone can prevent the development of opioid resistance, it has application in alleviating cancer-related pain that proves challenging to manage with other opioids. QT interval prolongation is a serious ...

    Authors: Ryusuke Ouchi, Munenori Nagao, Shinju Suzuki, Toshihiro Yamagata, Mie Chiba, Naoko Kurata, Kensuke Usui, Takashi Watanabe, Kaori Koyama and Kouji Okada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:4
    Content type: Case report Published on:

  10. Hemophilia is a rare genetic condition that is often overlooked and underdiagnosed, particularly in low-income countries. Long-term spontaneous joint bleeding and soft tissues can have a significant negative i...

    Authors: Sitina Iyar, Girma Tekle Gebremariam, Dessale Abate Beyene, Amha Gebremedhin and Tamrat Assefa Tadesse
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:3
    Content type: Research article Published on:

  11. Schizophrenia is a psychiatric disorder characterized by hallucinations, delusions, and other symptoms. Although treatment guidelines for schizophrenia have been established in Japan, drugs are not recommended...

    Authors: Daisuke Kikuchi, Taku Obara, Ryo Obara, Hiroaki Hino, Naoto Suzuki, Shota Kashiwagura, Takashi Watanabe, Ryusuke Ouchi, Kensuke Usui and Kouji Okada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:2
    Content type: Short report Published on:

  12. Bevacizumab is a monoclonal antibody against vascular endothelial growth factor. It has a wide range of clinical applications in various cancers and retinal diseases. The drugs entered the Chinese market by a ...

    Authors: Li Wang, Yibo Fei, Han Qu, Haiyang Zhang, Yuanyuan Wang, Zhenghua Wu and Guorong Fan
    Citation: Journal of Pharmaceutical Health Care and Sciences 2024 10:1
    Content type: Research article Published on:

  13. Pharmaceutical companies do not sell formulations for all diseases; thus, healthcare workers have to treat some diseases by concocting in-hospital preparations. An example is the high-concentration 2% cyclospo...

    Authors: Masakazu Ozaki, Toshihiko Kobayashi, Aki Fujinaga, Mitsuaki Nishioka, Kyoko Shikichi, Satoshi Okano, Yasuhito Sakai, Sayumi Fujii, Nobuaki Matsui, Miwako Takasago, Naoto Okada, Takahiro Yamasaki and Takashi Kitahara
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:50
    Content type: Research article Published on:

  14. Nucleoside analogues (NAs) such as entecavir are required for at least 12 months when patients with resolved hepatitis B virus (HBV) infection develop HBV reactivation. Entecavir treatment does not always achi...

    Authors: Maki Ohkubo, Kuniaki Fukuda, Shigeru Chiba and Masato Homma
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:52
    Content type: Case report Published on:

  15. We developed a bleeding risk scoring system (BRSS) using prophylactic anticoagulation therapy to comprehensively assess the risk of venous thromboembolism (VTE) in trauma patients. This study evaluated the use...

    Authors: Atsushi Tomizawa, Takaaki Maruhashi, Akito Shibuya, Akihiko Akamine, Masayuki Kuroiwa, Yuichi Kataoka, Yasushi Asari, Koichiro Atsuda and Katsuya Otori
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:48
    Content type: Research article Published on:

  16. Bleeding risk factors in elderly patients with atrial fibrillation undergoing percutaneous coronary intervention (PCI) are unclear and data on the use of antithrombotic drugs are lacking. We investigated the b...

    Authors: Kanako Fujita, Noriko Kohyama, Miki Sato, Tomokazu Deguchi, Hiroshi Suzuki, Mio Ebato and Mari Kogo
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:41
    Content type: Research article Published on:

  17. A reduction in the brain-derived neurotrophic factor (BDNF) level in the brain causes depression, whereas an increase in its level has therapeutic benefits against depression. BDNF is synthesized in various pe...

    Authors: Kensuke Nakajima, Shinya Okubo, Tomoe Ohta, Takuhiro Uto and Shigeru Oiso
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:40
    Content type: Research article Published on:

  18. Prescribing with high levels of medical appropriateness and patient satisfaction improves adherence. However, its appropriateness does not always match patient preference. Deprescription is important for ensur...

    Authors: Sayaka Arai, Takahiro Ishikawa, Kenichi Arai, Takaaki Suzuki and Itsuko Ishii
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:51
    Content type: Research article Published on:

  19. Our case is the first report showing the development of hypoglycemia following the administration of vadadustat in a patient with chronic kidney disease being treated with mitiglinide and sitagliptin, possibly...

    Authors: Ayumi Takakura, Toshinori Hirai, Naomi Hamaguchi, Rika Mukohara, Kazutaka Matsumoto, Yutaka Yano and Takuya Iwamoto
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:46
    Content type: Case report Published on:

  20. In most countries barring Japan, antihypertensive drug use has been reported using the defined daily doses/1000 inhabitants/day (DID). Although DID has been shown to allow for the assessment of the number of p...

    Authors: Kanako Mizuno, Ryo Inose, Yukina Yoshimura and Yuichi Muraki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:47
    Content type: Research article Published on:

  21. Long-term care issues, specifically metabolic bone disorders, are a concern for people living with human immunodeficiency virus (PLWH) who undergo life-long antiretroviral therapy (ART). Previous clinical tria...

    Authors: Yusuke Kunimoto, Ryosuke Matamura, Hiroshi Ikeda, Hiroto Horiguchi, Satoshi Fujii, Masayoshi Kobune, Masahide Fukudo and Takaki Toda
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:45
    Content type: Research article Published on:

  22. Methotrexate (MTX) is used to treat graft-versus-host disease (GVHD) following allogeneic hematopoietic stem cell transplantation (allo-HSCT). Recently, a case was encountered in which the blood concentration ...

    Authors: Chiaki Inoue, Takehito Yamamoto, Hiroshi Miyata, Hiroshi Suzuki and Tappei Takada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:38
    Content type: Research article Published on:

  23. Dexamethasone (DEX) induces CYP3A activity in a concentration-dependent manner. However, no study has examined changes in the blood concentration of CYP3A substrate drugs when DEX is administered at high doses...

    Authors: Yoshiyuki Ohno, Toyohito Oriyama, Akira Honda, Mineo Kurokawa and Tappei Takada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:39
    Content type: Case report Published on:

  24. Several methods have been reported for detecting resistance genes or phenotypic testing on the day of positive blood culture in Escherichia coli or Klebsiella pneumoniae bacteremia. However, some facilities have ...

    Authors: Mikiyasu Sakai, Takamasa Sakai, Yuki Nagata, Hiroko Komai, Yoshio Miyake, Toshitaka Watariguchi, Atsushi Kawabata and Fumiko Ohtsu
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:43
    Content type: Research article Published on:

  25. Suvorexant and ramelteon have been presented as useful for preventing postoperative delirium. Previous studies reported on the comparison with benzodiazepine hypnotics which have been known for the risk for in...

    Authors: Shoya Ikeuchi, Rei Tanaka, Teiichi Sugiura, Kaori Shinsato, Akane Wakabayashi, Junya Sato, Keiko Suzuki and Michihiro Shino
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:42
    Content type: Research article Published on:

  26. Gastrointestinal injuries caused by nonsteroidal anti-inflammatory drugs (NSAIDs) is a serious side effect in patients with rheumatoid arthritis (RA). However, effective therapeutic strategies have yet to be e...

    Authors: Saori Deguchi, Ayusa Iwakami, Mizuki Tujigiwa, Hiroko Otake, Yu Mano, Naoki Yamamoto, Yosuke Nakazawa, Manju Misra and Noriaki Nagai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:44
    Content type: Research article Published on:

  27. Drug therapy is a crucial aspect of heart failure management and has been shown to reduce morbidity and mortality in heart failure patients. However, the comparative effects of these drug classes on readmissio...

    Authors: Birhanu Ayenew, Prem Kumar, Adem Hussein, Yegoraw Gashaw, Mitaw Girma, Abdulmelik Ayalew and Beza Tadesse
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:49
    Content type: Research article Published on:

  28. Tedizolid is an oxazolidinone anti-MRSA drug with included in the National Health Insurance Drug Price List in 2018. The effect of hemodialysis on tedizolid phosphate concentrations has been reported; pre-dial...

    Authors: Satoshi Yoshikawa, Shinichi Yoshikawa, Akira Sato and Tsukasa Matsumoto
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:37
    Content type: Research article Published on:

  29. The loading dose of teicoplanin (TEIC) is recommended for implementation. However, there is significant discrepancy between the dose settings in the package insert and, in the guidelines, and the actual status...

    Authors: Ryota Goto, Yuichi Muraki, Ryo Inose, Moeno Ichii, Keisuke Sawada, Kanako Mizuno, Ryuji Koizumi, Shinya Tsuzuki, Masahiro Ishikane and Norio Ohmagari
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:35
    Content type: Research article Published on:

  30. We previously demonstrated that in a Japanese national university’s medical faculty, overall paper publication frequency increased between 1979–1980 and 2017–2018, while original paper publication did not inc...

    Authors: Theron Muller, Miho Takano and Nicole Gallagher
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:34
    Content type: Short report Published on:

  31. Tedizolid is a new oxazolidinone antibiotic with high potency for the treatment of infections caused by methicillin-resistant Staphylococcus aureus and other species.

    Authors: Daisuke Negishi, Okimichi Mitsumatsu, Hiromi Mitsumatsu, Miaki Makiguchi, Makiko Shimizu and Hiroshi Yamazaki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:33
    Content type: Case report Published on:

  32. Among Japanese pharmacists, there is a gap in their commitment to self-improvement and a possible gap in their ability to identify and solve problems. However, the factors causing this situation have not yet b...

    Authors: Keigo Watanabe, Takamasa Sakai and Fumiko Ohtsu
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:31
    Content type: Research article Published on:

  33. In-hospital therapeutic drug monitoring (TDM) requires a suitable quantification method for target drugs from the viewpoint of precision, throughput, and testing costs. We previously developed a practical HPLC...

    Authors: Go Morikawa, Kazuto Fukami, Yukiko Moriiwa, Katsuko Okazawa and Akio Yanagida
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:29
    Content type: Research article Published on:

  34. We conducted a systematic review and meta-analysis to summarize the available literature and comprehensively appraise the renal profiles of sodium-glucose cotransporter 2 inhibitors (SGLT2i) in Japanese patien...

    Authors: Junichi Mukai, Nakaba Okamura, Yuki Saito and Rie Kubota
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:36
    Content type: Research article Published on:

  35. Optimised antithrombotic therapy requires clinical experience and an understanding of the current guidelines. This retrospective study aimed to evaluate whether pharmacist interviews and interventions with pat...

    Authors: Tomoko Kurimura, Kazuhiro Yamamoto, Hidekazu Tanaka, Takayoshi Toba, Takeshi Kimura, Yasushi Habu, Kotaro Itohara, Yumi Kitahiro, Tomohiro Omura and Ikuko Yano
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:28
    Content type: Research article Published on:

  36. Enteral nutritional supplements are used in many medical facilities and home care, but require appropriate management because they are nutrient-rich products. Recently, infection control methods for Ready To H...

    Authors: Sachiko Omotani, Kanaha Murakami, Arisa Naka, Yasutoshi Hatsuda and Michiaki Myotoku
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:27
    Content type: Research article Published on:

  37. Epilepsy is a common neurological disorder. Lacosamide is a third-generation antiepileptic drug used to treat partial-onset seizures. Limited information is currently available on the transfer of lacosamide to...

    Authors: Ayako Furugen, Ayako Nishimura, Takeshi Umazume, Hina Ishikawa, Katsuya Narumi and Masaki Kobayashi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:26
    Content type: Research article Published on:

  38. Difficulty in taking solid medicines is a common issue particularly for the elderly because of a decline in swallowing function, also known as dysphagia. For patients with such a dysfunction, a simple suspensi...

    Authors: Ginjiro Kato, Hidemichi Mitome, Yusura Miyauchi, Syu Takeda, Yoshito Toyota, Noriaki Hidaka, Mamoru Tanaka and Kazuki Akira
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:32
    Content type: Research article Published on:

  39. Promoting stem cell donation behaviors could be crucial in advancing stem cell-based treatment, research and improving public health in Saudi Arabia. Donation of stem cells can be considered an act of social w...

    Authors: Asma Ayyed AL-Shammary and Sehar un-Nisa Hassan
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:30
    Content type: Research article Published on:

  40. Combination therapy with tazobactam/ceftolozane (TAZ/CTLZ) and high-dose aminoglycosides has been reported to be efficacious in extensively drug-resistant (XDR)-Pseudomonas aeruginosa infection. However, there ar...

    Authors: Yuta Ibe, Ryuichiro Kakizaki, Hirotoshi Inamura, Tomoyuki Ishigo, Yoshihiro Fujiya, Hiroyuki Inoue, Shuji Uemura, Satoshi Fujii, Satoshi Takahashi, Eichi Narimatsu and Masahide Fukudo
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:25
    Content type: Case report Published on:

  41. Olanzapine treatment prevents chemotherapy-induced nausea and vomiting (CINV) in patients receiving highly emetogenic chemotherapy (HEC). However, its role in the secondary prevention of breakthrough CINV in r...

    Authors: Akihiro Uchiike, Haruka Kono, Katsuhiro Miura, Tatsuya Hayama, Daisuke Tsutsumi, Shinya Tsuboi, Susumu Ohtsuka and Shinji Hidaka
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:24
    Content type: Research article Published on:

  42. In Japan, the use of risperidone in combination with adrenaline is contraindicated, except in cases of anaphylaxis. Therefore, there is limited clinical evidence regarding the interaction of these two drugs. H...

    Authors: Takafumi Nakano, Yoshihiko Nakamura, Keisuke Sato, Yoshito Izutani, Hiroto Iyota, Misaki Aoyagi, Taisuke Kitamura, Toshinobu Hayashi, Koichi Matsuo, Kenichi Mishima, Hidetoshi Kamimura, Hiroyasu Ishikura and Takashi Egawa
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:23
    Content type: Case report Published on:

  43. While cancer is a risk factor for developing thromboembolism, so is the use of molecularly targeted therapies. This study aimed to determine whether thromboembolism incidence differed between vascular endothel...

    Authors: Ryo Takada, Miki Fujiwara, Masatoshi Maki, Yoko Takahashi and Koji Tamura
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:22
    Content type: Short report Published on:

  44. The immersing powdered crude drugs (IPCD) method is a quick and simple method for preparing decoctions. Here, the conventional and IPCD methods were compared for the color and extraction of quantitative indica...

    Authors: Kazumasa Naruhashi, Natsumi Amaike, Karen Shiraishi, Sumire Sato, Chiho Uryuzu, Yui Saito and Narumi Tsue
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:21
    Content type: Research article Published on:

  45. It is important to design an effective formulation to enhance the skin penetration, and nanotechnologies have been used in dermal and transdermal drug delivery. In this study, we prepared formulations (gels) c...

    Authors: Reita Kadowaki, Fumihiko Ogata, Aoi Fushiki, Saki Daimyo, Saori Deguchi, Hiroko Otake, Mayumi Nagata, Hiroshi Sasaki, Naohito Kawasaki and Noriaki Nagai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:20
    Content type: Research article Published on:

  46. Insulin treatment is widely used not only for type 1 but also for type 2 diabetes patients. Insulin must be injected into the subcutaneous tissue to be effective. The needle length has been shortened for safet...

    Authors: Aya Torii-Goto, Kana Hirai, Yuri Inukai, Yoshimi Hoshina, Kazumi Shiomi, Junko Ito and Masae Yoshikawa
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:19
    Content type: Research article Published on:

  47. Erythrocyte transfusion is an indispensable component of supportive care after hematopoietic stem cell transplantation (HSCT). However, HSCT recipients are susceptible to the development of acute kidney injury...

    Authors: Hirokazu Nakayama, Yoshimasa Kamoda, Michiya Tanuma, Toshiaki Kato and Kensuke Usuki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:18
    Content type: Case report Published on:

  49. High-flow continuous hemodiafiltration (HF-CHDF) combines diffusive and convective solute removal and is employed for artificial liver adjuvant therapy. However, there is no report on dosage planning of vancom...

    Authors: Yuriko Ito, Junya Nakade, Akihiro Seki, Ryosuke Gabata, Mitsuyoshi Okazaki, Shinichi Nakanuma, Arimi Fujita, Tsutomu Shimada, Taro Yamashita, Shintaro Yagi, Takumi Taniguchi and Yoshimichi Sai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:15
    Content type: Case report Published on:

  50. Alectinib, crizotinib, and ceritinib, are anaplastic lymphoma kinase-tyrosine kinase inhibitors (ALK-TKIs) that exhibit high protein binding, and their metabolism is associated with the cytochrome P450 (CYP) i...

    Authors: Takashi Kato, Yusuke Kunimoto, Manabu Kitagawa, Yuichiro Asai, Tomoko Kimyo, Hiromasa Nakata, Mamoru Takahashi, Hirofumi Chiba, Hiroki Takahashi, Atsushi Miyamoto and Masahide Fukudo
    Citation: Journal of Pharmaceutical Health Care and Sciences 2023 9:14
    Content type: Case report Published on:
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  • Citation Impact 2023
    Journal Impact Factor: 1.2
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    Source Normalized Impact per Paper (SNIP): 0.557
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Journal of Pharmaceutical Health Care and Sciences

ISSN: 2055-0294

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