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  1. The accuracy, safety and feasibility of, the compounding robot APOTECAchemo were evaluated in the clinical practice of Japan.

    Authors: Takuya Iwamoto, Takuya Morikawa, Miki Hioki, Hirofumi Sudo, Demis Paolucci and Masahiro Okuda
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:12
  2. With the development of pharmacotherapy and radiotherapy, cancer treatment is being shifted from surgical to outpatient services, consequently increasing insurance-covered pharmacies’ frequency of dealing with...

    Authors: Manako Hanya, Yoshitake Kanno, Junko Akasaki, Keiko Abe, Kazuhiko Fujisaki and Hiroyuki Kamei
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:11
  3. Authors: Kenta Shibata, Yuuki Akagi, Naofumi Nozawa, Hitoshi Shimomura and Takao Aoyama
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:10

    The original article was published in Journal of Pharmaceutical Health Care and Sciences 2017 3:9

  4. Low-dose aspirin irreversibly inhibits platelet cyclooxygenase-1 (COX-1) and suppresses platelet aggregation. It is effective for secondary prevention of cardiovascular events. Because nonsteroidal anti-inflam...

    Authors: Kenta Shibata, Yuuki Akagi, Naofumi Nozawa, Hitoshi Shimomura and Takao Aoyama
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:9

    The Erratum to this article has been published in Journal of Pharmaceutical Health Care and Sciences 2017 3:10

  5. Nosocomial infection is one of the most common complications within health care facilities. Certain studies have reported outbreaks resulting from contaminated hospital environments. Although the identificatio...

    Authors: Akihiro Manaka, Yutaka Tokue and Masami Murakami
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:8
  6. Methotrexate (MTX) and salazosulfapyridine (SASP) are disease-modifying drugs that are commonly used in the treatment of rheumatoid arthritis (RA), and combination therapy with MTX and SASP is recommended for ...

    Authors: Morihiro Okada, Hiroshi Fujii, Yukio Suga, Satoshi Morito, Masae Okada, Jun Nishigami, Mitsuhiro Kawano, Tsutomu Shimada and Yoshimichi Sai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:7
  7. The aims of this study were to investigate predictive factors involved in effectiveness and safety of enoxaparin for prevention of postoperative venous thromboembolism in aged Japanese total knee arthroplasty ...

    Authors: Akihiro Sonoda, Yuki Kondo, Yasuhiro Tsuneyoshi, Yoshitaka Iwashita, Shoji Nakao, Kazuhisa Ishida, Kentaro Oniki, Junji Saruwatari, Tetsumi Irie and Yoichi Ishitsuka
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:6
  8. An optimal inhalation flow pattern is essential for effective use of a dry powder inhaler (DPI). We wondered whether DPI instructors inhale from a DPI with an appropriate pattern, and if not, whether self-trai...

    Authors: Tetsuri Kondo, Makoto Hibino, Toshimori Tanigaki, Stanley M. Cassan, Sakurako Tajiri and Kenichro Akazawa
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:5
  9. Appropriate prescription of dabigatran etexilate methanesulfonate (JAN) is more complicated than assumed, because there are totally 10 items of contraindications and instructions for dosage reduction depending...

    Authors: Teppei Shimizu, Yoshio Momose, Ryuichi Ogawa, Masahiro Takahashi and Hirotoshi Echizen
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:4
  10. Bladder cancer patients receiving methotrexate, vinblastine, adriamycin and cisplatin (MVAC) chemotherapy are co-administered with dexamethasone as an anti-emetic. We examined whether or not dexamethasone affe...

    Authors: Shingo Itai, Yukio Suga, Yusuke Hara, Kouji Izumi, Yuji Maeda, Yasuhide Kitagawa, Junko Ishizaki, Tsutomu Shimada, Atsushi Mizokami and Yoshimichi Sai
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:3
  11. Medication self-management in stroke patients is important to prevent further progression of disease and incidence of side effects. The purpose of this study was to create a formula for predicting medication s...

    Authors: Hisato Fujihara, Mari Kogo, Isao Saito, Nobuyuki Kawate, Masazumi Mizuma, Hiroko Suzuki, Jun-ichiro Murayama and Tadanori Sasaki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:2
  12. Few studies have reported the dosage of cefmetazole (CMZ) for intraoperative antimicrobial prophylaxis in patients underwent surgery for colorectal cancer. We therefore examined the optimal intraoperative dosa...

    Authors: Atsushi Tomizawa, Takatoshi Nakamura, Toshiaki Komatsu, Hiroshi Inano, Rumiko Kondo, Masahiko Watanabe and Koichiro Atsuda
    Citation: Journal of Pharmaceutical Health Care and Sciences 2017 3:1
  13. Methotrexate (MTX) is currently the anchor drug widely used worldwide in the treatment of rheumatoid arthritis (RA). However, the therapeutic response to MTX has been shown to vary widely among individuals, ge...

    Authors: Masayuki Hashiguchi, Mikiko Shimizu, Jun Hakamata, Tomomi Tsuru, Takanori Tanaka, Midori Suzaki, Kumika Miyawaki, Takeshi Chiyoda, Osamu Takeuchi, Jiro Hiratsuka, Shin Irie, Junya Maruyama and Mayumi Mochizuki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:35
  14. Hyperphosphatemia is one of the common complications in patients undergoing hemodialysis. Although calcium carbonate (CaC) is often used to control serum inorganic phosphorus level in dialysis patients, co-adm...

    Authors: Masaomi Tatsuzawa, Ryuichi Ogawa, Atsushi Ohkubo, Kazuyo Shimojima, Kunimi Maeda, Hirotoshi Echizen and Akihisa Miyazaki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:34
  15. There are currently no promising therapies available to treat or prevent peripheral neuropathy (PN) induced by anticancer drugs in a cumulative dose-dependent manner. In this study, we investigated the efficac...

    Authors: Junya Sato, Megumi Mori, Satoru Nihei, Masumi Kumagai, Satoshi Takeuchi, Masahiro Kashiwaba and Kenzo Kudo
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:33
  16. The coreceptor tropism testing should be conducted prior to commencing a regimen containing a CCR5 antagonist for treatment of HIV-1 infection. For aviremic patients on long antiretroviral therapy, proviral DN...

    Authors: Hiroshi Kotani, Koji Sudo, Naoki Hasegawa, Hiroshi Fujiwara, Tomohisa Hayakawa, Osamu Iketani, Masaya Yamaguchi, Mayumi Mochizuki, Satoshi Iwata and Shingo Kato
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:31
  17. Consideration of medical costs as well as effectiveness and adverse events is rapidly been becoming an important factor in the selection of chemotherapy regimens. However, practical data on the costs of chemot...

    Authors: Kosuke Takata, Ken-ichi Fujita, Yutaro Kubota, Hiroo Ishida, Wataru Ichikawa, Ken Shimada, Takashi Sekikawa, Iori Taki-Takemoto, Daisuke Kamei, Shinichi Iwai and Yasutsuna Sasaki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:30
  18. Pregabalin is recommended as an adjuvant analgesic for neuropathic cancer-related pain, and may be taken at all steps of the World Health Organization analgesic ladder. However, unlike opioids, pregabalin trea...

    Authors: Ryo Yajima, Kazuaki Matsumoto, Yuya Ise, Norihito Suzuki, Yuta Yokoyama, Junko Kizu and Shiro Katayama
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:29
  19. The exposure of healthcare workers to anticancer drugs such as cyclophosphamide (CPA) is a serious health concern. Anticancer drug pollution may spread outside biological safety cabinets even when a closed sys...

    Authors: Junya Sato, Atushi Kogure and Kenzo Kudo
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:28
  20. It is well-documented that chronic kidney disease (CKD) often results in end-stage renal failure and puts patients at extremely high risk for developing cardiovascular disease. Educational hospitalization at m...

    Authors: Eiji Kose, Taesong An, Akihiko Kikkawa and Hiroyuki Hayashi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:27
  21. Exposure to anticancer drugs is hazardous and may lead to chromosomal abnormalities and spontaneous abortion in healthcare workers. Guidelines recommend surface decontamination and cleaning in order to minimiz...

    Authors: Ayumi Tsukamoto, Shunji Ishiwata, Asami Kajimoto, Ryusuke Murata, Rika Kitano, Tomomi Inoue and Takeshi Kotake
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:26
  22. This study aimed to develop a simultaneous determination method for tramadol and its desmethylates in human plasma using isocratic liquid chromatography coupled to tandem mass spectrometry and to validate it f...

    Authors: Hironari Tanaka, Takafumi Naito, Yasuaki Mino and Junichi Kawakami
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:25
  23. Taxanes are known to cause onychopathy. Previous studies have reported the relationship between onychopathy and paclitaxel dosing intervals and cumulative doses. However, there are no studies of the predictive...

    Authors: Hidenobu Takahata, Kouichi Tanabe, Akiyoshi Takaki, Tsuneaki Yamanouchi, Yasuhiko Mimura, Atsumi Nitta, Hatsuna Yasuda, Tatsuhiko Kashii and Isao Adachi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:24
  24. Hypomagnesemia is one of the characteristic side effects of the human anti-epidermal growth factor receptor (EGFR) monoclonal antibodies, cetuximab and panitumumab.

    Authors: Toshiyasu Tsujii, Takafumi Ogaki, Kaori Nakae, Kiyotaka Imai, Daisuke Kise, Shoji Tada, Hiroki Ueda and Masahiro Moriyama
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:23
  25. Plasma tenofovir (TFV) trough concentrations may be relevant for tenofovir disoproxil fumarate (TDF)-induced renal dysfunction. The purpose of this study was to determine the association between plasma TFV tro...

    Authors: Yusuke Kunimoto, Hiroshi Ikeda, Satoshi Fujii, Manabu Kitagawa, Kieko Yamazaki, Hiromasa Nakata, Norimasa Noda, Tadao Ishida and Atsushi Miyamoto
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:22
  26. A new formulation of olanzapine available for terminally ill patients is needed. Rectal administration using suppositories is an alternative for patients for whom administration via the oral route is not feasi...

    Authors: Kazuaki Matsumoto, Satoru Kimura, Kenichi Takahashi, Yuta Yokoyama, Masayuki Miyazawa, Satoko Kushibiki, Morio Katamachi and Junko Kizu
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:20
  27. Many pharmacists are participating in team-based medical care in emergency hospitals. Therefore, there is a desperate need to improve the education system. In the present study, we provided a “pharmaceutical l...

    Authors: Yoshito Zamami, Toru Imai, Masaki Imanishi, Kenshi Takechi, Naoko Shiraishi, Toshihiro Koyama, Hidenori Sagara, Yasukazu Shiino, Toshiaki Sendo and Keisuke Ishizawa
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:21
  28. Sivelestat, a neutrophil elastase inhibitor, was previously approved in Japan for the treatment of acute lung injury associated with systemic inflammatory response syndrome. However, sivelestat produced incons...

    Authors: Takuma Ozawa, Kiyoshi Mihara and Nobuhiro Yasuno
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:19
  29. We investigated the pharmacokinetics of etoposide (ETP) to reduce the inter-individual variations of ETP concentrations in patients with acute leukemia who underwent allogeneic hematopoietic stem cell transpla...

    Authors: Yuki Tazawa, Akio Shigematsu, Kumiko Kasashi, Junichi Sugita, Tomoyuki Endo, Takeshi Kondo, Takanori Teshima, Ken Iseki, Mitsuru Sugawara and Yoh Takekuma
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:18
  30. Catheter ablation is a non-medication therapy for atrial fibrillation, and during the procedure, warfarin is withdrawn in the preoperative period to prevent the risk of bleeding. In case of emergency, vitamin K2 ...

    Authors: Zhi Zhou, Ikuko Yano, Sumiko Odaka, Yosuke Morita, Satoshi Shizuta, Mamoru Hayano, Takeshi Kimura, Akinori Akaike, Ken-ichi Inui and Kazuo Matsubara
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:17
  31. Genotype frequencies for chemotherapy-induced nausea and vomiting (CINV)-related polymorphisms have not yet been reported for Japanese subjects.

    Authors: Aya Goto, Haruka Kotani, Masayuki Miyazaki, Kiyofumi Yamada, Kazuhiro Ishikawa, Yasuhiko Shimoyama, Toshimitsu Niwa, Yoshinori Hasegawa and Yukihiro Noda
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:16
  32. Regorafenib and its metabolites may inhibit the activities of several CYP or UDP-glucuronosyltransferase isoforms, including that of CYP2C9. Therefore, pharmacological agents that are CYP2C9 substrates may sho...

    Authors: Hironori Kitade, Azusa Hiromasa-Yamasaki, Kengo Hokkoku, Mitsue Mori, Michio Watanabe, Masuo Nakai and Seiji Yano
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:15
  33. Stevens-Johnson syndrome (SJS) and toxic epidermal necrolysis (TEN) are severe cutaneous adverse reactions associated with fatal disorders. Although many causes of SJS/TEN have been proposed, the time-to-onset...

    Authors: Junko Abe, Ryogo Umetsu, Kanako Mataki, Yamato Kato, Natsumi Ueda, Yoko Nakayama, Yuuki Hane, Toshinobu Matsui, Haruna Hatahira, Sayaka Sasaoka, Yumi Motooka, Hideaki Hara, Zenichiro Kato, Yasutomi Kinosada, Naoki Inagaki and Mitsuhiro Nakamura
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:14
  34. Rheumatoid arthritis (RA) is a chronic autoimmune disease characterized by systemic inflammatory status, joint destruction, disability, and pain. Methotrexate (MTX) has been confirmed to reduce disease activit...

    Authors: Masayuki Hashiguchi, Tomomi Tsuru, Kumika Miyawaki, Midori Suzaki, Jun Hakamata, Mikiko Shimizu, Shin Irie and Mayumi Mochizuki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:13
  35. We formulated mianserin suppositories for the treatment of delirium and evaluated their pharmacokinetics by measuring plasma drug concentrations in dogs and healthy human volunteers.

    Authors: Shuichi Nawata, Noriko Kohyama, Naoki Uchida, Satoshi Numazawa, Masayuki Ohbayashi, Yasuna Kobayashi, Masanori Iwata, Takanori Nakajima, Hiroshi Saito, Akira Izuka and Toshinori Yamamoto
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:12
  36. Osteoporosis is estimated to afflict over 200 million people worldwide and healthcare professionals are needed to successfully intervene. The aim of this study was to assess cognitive changes in students perta...

    Authors: Erisa Tomishige-Mukai, Akio Kawachi, Erika Kiyohara, Fuminori Esaki, Junichiro Sonoda, Tomohiro Shinya, Keiko Narumi, Keizo Sato and Toshiro Motoya
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:11
  37. Voriconazole concentrations display a large variability, which cannot completely be explained by known factors. We investigated the relationships of voriconazole concentration with patient-specific variables a...

    Authors: Satoshi Dote, Maki Sawai, Ayumu Nozaki, Kazumasa Naruhashi, Yuka Kobayashi and Hirokazu Nakanishi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:10
  38. This study was designed to evaluate the population pharmacokinetics (popPK) of penicillin G in patients with infective endocarditis and establish a dosage regimen based on pharmacokinetic data and clinical out...

    Authors: Toshiaki Komatsu, Takayuki Inomata, Ichiro Watanabe, Masahiro Kobayashi, Hideya Kokubun, Junya Ako and Koichiro Atsuda
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:9
  39. The increased risk of new-onset diabetes with statin use, including high-potency statins, is well known. However, the effects of high-potency statins on HbA1c are unclear. A retrospective cohort study was cond...

    Authors: Nobuhiro Ooba, Shoutarou Tanaka, Yu Yasukawa, Nariyasu Yoshino, Hiroyuki Hayashi, Shinji Hidaka, Toshiichi Seki and Noriyasu Fukuoka
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:8
  40. High-dose methotrexate (HDMTX) is used in the treatment of certain malignancies, including leptomeningeal metastases, systemic non-Hodgkin lymphoma, acute lymphoblastic leukemia, and osteosarcoma. High circula...

    Authors: Tetsuya Kaneko, Takashi Fujioka, Yosuke Suzuki, Yuhki Sato and Hiroki Itoh
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:7
  41. Cisplatin (CDDP) is used as a key anticancer drug for solid cancers, including lung cancer. However, a large quantity of fluid replacement is required to prevent renal dysfunction. This requirement have made o...

    Authors: Junya Sato, Naoto Morikawa, Hiroo Nitanai, Hiromi Nagashima, Satoru Nihei, Kohei Yamauti and Kenzo Kudo
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:6
  42. Atropine sulfate is an anticholinergic agent for treatment of hypertrophic pyloric stenosis and is orally administrated as a triturate with lactose hydrate. Because of the low safety margin of atropine sulfate...

    Authors: Kei Moriyama, Yoichiro Takami, Natsuki Uozumi, Akiko Okuda, Mayumi Yamashita, Rie Yokomizo, Kenichi Shimada, Takashi Egawa, Takehito Kamei and Kazunobu Takayanagi
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:4
  43. Debate continues about the optimal anticoagulation level for elderly Japanese patients with non-valvular atrial fibrillation (NVAF) receiving warfarin. The Japanese Circulation Society guideline has recommende...

    Authors: Atsushi Ohgushi, Takayuki Ohtani, Natsumi Nakayama, Shigeo Asai, Yoshiyuki Ishii, Atsuo Namiki, Manabu Akazawa and Hirotoshi Echizen
    Citation: Journal of Pharmaceutical Health Care and Sciences 2016 2:2
  44. Bisphosphonates (BPs) are potent antiresorptive agents used to treat osteoporosis and the complications associated with malignant bone metastasis. The aim of this study was to evaluate the incidence of bisphos...

    Authors: Mitsuhiro Nakamura, Ryogo Umetsu, Junko Abe, Toshinobu Matsui, Natsumi Ueda, Yamato Kato, Sayaka Sasaoka, Kohei Tahara, Hirofumi Takeuchi and Yasutomi Kinosada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:34
  45. Increasing the use of generic drugs may reduce the growing healthcare spending. Nevertheless, in Japan, the generic drug market share remains low compared to that of European countries and the United States, m...

    Authors: Masanori Suzuki, Motoyasu Kanamori, Tomoaki Hashimoto, Yuji Hashimoto, Ryohkan Funakoshi and Tadanori Sasaki
    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 2:1
  46. The implementation of a protocol has been associated with improvements in the processes of care in clinical settings. Although stress ulcer prophylaxis is recommended for critically ill patients at high risk, ...

    Authors: Mai Ikemura, Shinji Nakasako, Ryutaro Seo, Takahiro Atsumi, Koichi Ariyoshi and Tohru Hashida
    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:33
  47. Pregabalin, a gabapentinoid, is an adjuvant analgesic for treatment of neuropathic pain, but it has serious adverse effects such as somnolence and dizziness, particularly in elderly patients. Although decrease...

    Authors: Akihiro Ohishi, Yugo Chisaki, Daiki Hira, Kazuki Nagasawa and Tomohiro Terada
    Citation: Journal of Pharmaceutical Health Care and Sciences 2015 1:30

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